Homeodomain Proteins
Research News and Information

Saturday, November 21, 2009

OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells.

29 Nov 2009 In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or ... Read more...

Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy.

29 Nov 2009 Transforming growth factor-beta (TGF-beta) is a cytokine with potent immunosuppressive effects and is overexpressed in many tumors. Therefore, development of molecules able to inhibit TGF-beta is of paramount importance to improve the efficacy of ... Read more...

Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain.

8 Nov 2009 NKX3.1 is a prostate tumor suppressor belonging to the NK-2 family of homeodomain (HD) transcription factors. NK-2 family members often possess a stretch of 10-15 residues enriched in acidic amino acids, the acidic domain (AD), in the flexible, ... Read more...

Latest indexed articles for 'Homeodomain Proteins'

These are the very latest articles for this heading:

• OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells. 29 Nov 2009
• Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy. 29 Nov 2009
• Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain. 8 Nov 2009
• Fusion of EWSR1 with the DUX4 facioscapulohumeral muscular dystrophy region resulting from t(4;22)(q35;q12) in a case of embryonal rhabdomyosarcoma. 30 Oct 2009
• Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event. 30 Oct 2009
• In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue. 30 Oct 2009
• HOXA methylation in normal endometrium from premenopausal women is associated with the presence of ovarian cancer: a proof of principle study. 30 Oct 2009
• Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10. 13 Oct 2009
• Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. 12 Oct 2009
• A lymphotoxin-driven pathway to hepatocellular carcinoma. 4 Oct 2009
• Retinal input instructs alignment of visual topographic maps. 30 Sep 2009
• Addressing Alzheimer's disease tangles: from NAP to AL-108. 29 Sep 2009
• NK cells protect secondary lymphoid tissue from cytomegalovirus via a CD30-dependent mechanism. 29 Sep 2009
• IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4(+) memory T cells in chronic colitis. 29 Sep 2009
• Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis. 29 Sep 2009
• Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos. 29 Sep 2009
• More than patterning--Hox genes and the control of posterior axial elongation. 29 Sep 2009
• Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration. 29 Sep 2009
• CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. 29 Sep 2009
• Regulation of CDX2 expression in esophageal adenocarcinoma. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Homeodomain Proteins'

Definition: Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).

Registry Number: 0

Descriptor UI: D018398

Alternative terms: Homeodomain Proteins; Proteins, Homeodomain; Homeobox Proteins; Proteins, Homeobox; Homeotic Proteins; Proteins, Homeotic; Homeoproteins; Homeo Domain Proteins; Proteins, Homeo Domain;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.400;

History Note: 95

Technical Notes: DNA-binding proteins