HSP47 Heat-Shock Proteins
Research News and Information

Sunday, November 22, 2009

Renal tubular expression of Toll-like receptor 4 in cyclosporine nephrotoxicity.

30 Jul 2009 Exploring the expression of Toll-like receptor (TLR) in cyclosporine (CsA)-induced renal injury in humans, we evaluated the expression of TLR4 in both biopsied renal tissue and cultured tubular cells. Immunohistochemical stains for TLR4, heat shock ... Read more...

A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta.

22 Jul 2009 Osteogenesis imperfecta (OI) is a hereditary disease occurring in humans and dogs. It is characterized by extremely fragile bones and teeth. Most human and some canine OI cases are caused by mutations in the COL1A1 and COL1A2 genes encoding the ... Read more...

Development of a high-throughput screening system for the compounds that inhibit collagen-protein interactions.

13 Jul 2009 Collagen-binding proteins (CBPs) play important roles in various physiological events. Some CBPs are regarded as targets for drug development; for example, platelet glycoprotein VI (GPVI) and heat shock protein 47 (HSP47) are promising targets for ... Read more...

Latest indexed articles for 'HSP47 Heat-Shock Proteins'

These are the very latest articles for this heading:

• Renal tubular expression of Toll-like receptor 4 in cyclosporine nephrotoxicity. 30 Jul 2009
• A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta. 22 Jul 2009
• Development of a high-throughput screening system for the compounds that inhibit collagen-protein interactions. 13 Jul 2009
• High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach. 12 Jul 2009
• Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats. 22 Jun 2009
• A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets. 30 May 2009
• Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice. 18 May 2009
• Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. 6 Apr 2009
• The plasmid encoding HSP47 enhances collagen expression and promotes skin wound healing in an alloxan-induced diabetic model. 2 Mar 2009
• Remodeling of the rat gingiva induced by CO2 laser coagulation mode. 29 Nov 2008
• Renoprotective effect of azelnidipine in rats. 29 Nov 2008
• High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis. 2 Nov 2008
• Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression. 22 Oct 2008
• Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye. 16 Jul 2008
• Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing. 30 May 2008
• Stress response of mammalian cells incubated with landfill leachate. 29 Apr 2008
• Novel adenoviral gene delivery system targeted against head and neck cancer. 30 Mar 2008
• Expression of heat shock protein 47 in the periodontal ligament during orthodontic tooth movement. 19 Mar 2008
• A 12-bp deletion in the 5'-flanking region of the SERPINH1 gene affects promoter activity and protects against preterm premature rupture of membranes in African Americans. 30 Jan 2008
• The upregulation of heat shock protein 47 expression in human buccal fibroblasts stimulated with arecoline. 20 Jan 2008

See a longer list of these articles.

Technical information about 'HSP47 Heat-Shock Proteins'

Definition: Basic glycoprotein members of the SERPIN SUPERFAMILY that function as COLLAGEN-specific MOLECULAR CHAPERONES in the ENDOPLASMIC RETICULUM.

Registry Number: 0

Descriptor UI: D050958

Alternative terms: HSP47 Heat-Shock Proteins; HSP47 Heat Shock Proteins; Heat-Shock Proteins, HSP47; Proteins, HSP47 Heat-Shock; Heat-Shock Protein 47; Heat Shock Protein 47;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.410.295; D12.776.580.220; D12.776.872.350;

History Note: 2006(1993)