Human Experimentation
Research News and Information

Saturday, November 21, 2009

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers.

29 Sep 2009 Our objectives were to compare the pharmacokinetics (PK) of carumonam, a monobactam, between cystic fibrosis (CF) patients and healthy volunteers and assess its pharmacodynamic profile. We studied 10 adult CF patients and 18 healthy volunteers of ... Read more...

Determination of new cutoff values for indirect immunofluorescence antibody test for Q fever diagnosis in Denmark.

29 Sep 2009 Q fever is a ubiquitous zoonosis caused by Coxiella burnetii. The disease is emerging in many parts of the world, likely because of increased awareness and availability of better diagnostics. The diagnosis is primarily based on serology. Because the ... Read more...

Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11).

6 Sep 2009 BACKGROUND: The treatment of patients with haematological malignancies by means of haematopoietic stem cell transplantation (HSCT) is often accompanied by life threatening infections. With emerging antimicrobial resistance there is an increased need ... Read more...

Latest indexed articles for 'Human Experimentation'

These are the very latest articles for this heading:

• Should healthy volunteers in clinical trials be paid according to risk? No. 20 Oct 2009
• Should healthy volunteers in clinical trials be paid according to risk? Yes. 20 Oct 2009
• Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers. 29 Sep 2009
• Determination of new cutoff values for indirect immunofluorescence antibody test for Q fever diagnosis in Denmark. 29 Sep 2009
• Bioengineered bodies and the moral imagination. 17 Sep 2009
• Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11). 6 Sep 2009
• Rethinking the responsiveness requirement for international research. 3 Sep 2009
• Nitric oxide inhalation and glucocorticoids as combined treatment in human experimental endotoxemia: It takes not always two to tango. 30 Aug 2009
• Perspectives on human stem cell research. 30 Aug 2009
• Research with vulnerable human beings. 18 Aug 2009
• Compensation for incarcerated research participants: diverse state policies suggest a new research agenda. 18 Aug 2009
• An ethics perspective on responsibilities of investigators, sponsors and research participants. 6 Aug 2009
• Ethical principles in health research and review process. 5 Aug 2009
• Development of the volunteer peer educator role in a community Cardiovascular Health Awareness Program (CHAP): a process evaluation in two communities. 30 Jul 2009
• Clinical research law in Jordan. 30 Jul 2009
• Shared and persistent asymptomatic cutaneous human papillomavirus infections in healthy skin. 30 Jul 2009
• Safety and immunogenicity of an indigenously developed Haemophilus influenzae type b conjugate vaccine through various phases of clinical trials. 29 Jul 2009
• TLR expression and NK cell activation after human yellow fever vaccination. 28 Jul 2009
• It is critical that the welfare of research participants who enable such research activities to be conducted is protected during and after the studies. Foreword. 28 Jul 2009
• The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans. 25 Jul 2009

See a longer list of these articles.

Technical information about 'Human Experimentation'

Definition: The use of humans as investigational subjects.

Descriptor UI: D006805

Alternative terms: Human Experimentation; Experimentation, Human; Human Volunteers; Human Volunteer; Volunteer, Human; Volunteers, Human;

Related Mesh Headings: Helsinki Declaration; Bioethical Issues; Ethics, Research; Embryo Research; Fetal Research; Research Subjects;

Allowable Qualifiers: ethics; history; legislation & jurisprudence; statistics & numerical data; standards;

Tree Number: E05.445;

History Note: 66

Technical Notes: IM for moral, legal, ethical, sociologic, religious aspect of experiments on humans; coordinate IM with aspect (IM); do not routinely add for research involving human disease, therapy or physiology