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Human Growth Hormone - Research News and Information

Saturday, January 10, 2009

Definition of 'Human Growth Hormone'

A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.

Common names: Human Growth Hormone; Growth Hormone, Human; Somatotropin (Human); Somatropin (Human); hGH (Human Growth Hormone); Somatropin; Genotropin; Pharmacia Brand of Human Growth Hormone; Pharmacia Spain Brand of Human Growth Hormone; Genotonorm; Humatrope; Umatrope; Lilly Brand of Human Growth Hormone

More technical Information...

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial.

2 Nov 2008 BACKGROUND: Growth hormone secretion and muscle mass decline from midpuberty throughout life, culminating in sarcopenia, frailty, decreased function, and loss of independence. The decline of growth hormone in the development of sarcopenia is one of ... Read more...


Immunohistochemical expression of SNAP-25 protein in adenomas of the human pituitary.

29 Sep 2008 SNAP-25, a synaptosome-associated exocytosis protein of 25 kd mw, plays an important role in the secretory activity of several endocrine cells. In the present study, we investigated surgically removed pituitary adenomas including 40 prolactin ... Read more...


Analysis of Cibacron blue F3G-A interaction with therapeutic proteins by MALDI-TOF mass spectrometry.

30 Aug 2008 The formation of the complexes between Cibacron blue F3G-A and two therapeutic proteins, recombinant human interferon-alpha2b and recombinant human growth hormone, was investigated. The method of time-resolved limited proteolysis coupled with ... Read more...

 

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Technical information about 'Human Growth Hormone'

Definition: A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.

Chemical name: Somatotropin (human)

Registry Number: 12629-01-5

Descriptor UI: D019382

Alternative terms: Human Growth Hormone; Growth Hormone, Human; Somatotropin (Human); Somatropin (Human); hGH (Human Growth Hormone); Somatropin; Genotropin; Pharmacia Brand of Human Growth Hormone; Pharmacia Spain Brand of Human Growth Hormone; Genotonorm; Humatrope; Umatrope; Lilly Brand of Human Growth Hormone; Eli Lilly Brand of Human Growth Hormone; Irisfarma Brand of Human Growth Hormone; Maxomat; Sanofi Synthelabo Brand of Human Growth Hormone; Norditropin; Pisa Brand of Human Growth Hormone; Novo Nordisk Brand of Human Growth Hormone; Norditropin Simplexx; Norditropine; Zomacton; Ferring Brand of Human Growth Hormone; Omnitrope; Sandoz Brand of Human Growth Hormone; Recombinant Human Growth Hormone (Mammalian); r-hGH-M; r-hGH(m); Saizen; Allphar Brand of Human Growth Hormone; Serostim; Serono Brand of Human Growth Hormone; Cryo-Tropin; Cryo Tropin; CryoTropin; Cryopharma Brand of Human Growth Hormone; Nutropin; Hoffmann La-Roche Brand of Human Growth Hormone; Hoffmann La Roche Brand of Human Growth Hormone;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D06.472.699.631.525.425.875; D12.644.548.691.525.425.875;

History Note: 2003 (1997); for SEROSTIM use SOMATOTROPINS, RECOMBINANT (NM) 1996-2002; use NORDITROPIN (NM) 1992-1996

Technical Notes: GROWTH HORMONE, unspecified is also available; despite entry term, coordinate with RECOMBINANT PROTEINS for recombinant human growth hormone

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