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Huntington Disease - Psychology
Research News and Information
Definition of 'Huntington Disease'A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4) |
Sunday, November 22, 2009
7 Jun 2009
OBJECTIVE: To assess the nature and prevalence of genetic discrimination experienced by people at risk for Huntington's disease who had undergone genetic testing or remained untested. DESIGN: Cross sectional, self reported survey. SETTING: Seven ... Read more...
Not on the face alone: perception of contextualized face expressions in Huntington's disease.
16 May 2009
Numerous studies have demonstrated that Huntington's disease mutation-carriers have deficient explicit recognition of isolated facial expressions. There are no studies, however, which have investigated the recognition of facial expressions embedded ... Read more...
Is there a duty to share genetic information?
29 Apr 2009
A number of prominent bioethicists, such as Parker, Lucassen and Knoppers, have called for the adoption of a system in which by default genetic information is shared among family members. This paper suggests that a main reason given in support of ... Read more...
Latest indexed articles for 'Huntington Disease - Psychology'
These are the very latest articles for this heading:
- Genetic discrimination in Huntington's disease.
7 Jun 2009 - Perceptions of genetic discrimination among people at risk for Huntington's disease: a cross sectional survey.
7 Jun 2009 - Not on the face alone: perception of contextualized face expressions in Huntington's disease.
16 May 2009 - Is there a duty to share genetic information?
29 Apr 2009 - Dementia and suicidal behavior: a review of the literature.
14 Apr 2009 - Functional compensation of motor function in pre-symptomatic Huntington's disease.
13 Apr 2009 - Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance.
26 Mar 2009 - Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington's disease.
26 Mar 2009 - How young people find out about their family history of Huntington's disease.
24 Mar 2009 - [Suicide in Huntington's disease: a review]
16 Mar 2009 - Health-related quality of life in Huntington's disease: Which factors matter most?
13 Mar 2009 - Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin.
16 Feb 2009 - The impact of an intense religious experience on motor symptoms in Huntington's disease.
13 Feb 2009 - An intergenerational contraction of a fully penetrant Huntington disease allele to a reduced penetrance allele: interpretation of results and significance for risk assessment and genetic counseling.
13 Feb 2009 - Psychiatric expertise for a multidisciplinary Huntington's disease clinic.
30 Jan 2009 - Increased hypothalamic-pituitary-adrenal axis activity in Huntington's disease.
25 Jan 2009 - Tetrabenazine (Xenazine) for Huntington's chorea.
24 Jan 2009 - [A female patient with late-onset schizophrenia and fear of Katwijk disease]
30 Dec 2008 - Cognitive and limbic circuits that are affected by deep brain stimulation.
30 Dec 2008 - Cognitive and limbic effects of deep brain stimulation in preclinical studies.
30 Dec 2008
See a longer list of these articles.
Technical information about 'Huntington Disease'
Definition: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Descriptor UI: D006816
Alternative terms: Huntington Disease; Huntington Chorea; Chorea, Huntington; Huntington's Disease; Chronic Progressive Hereditary Chorea (Huntington); Huntington Chronic Progressive Hereditary Chorea; Progressive Chorea, Chronic Hereditary (Huntington); Progressive Chorea, Hereditary, Chronic (Huntington); Huntington's Chorea; Chorea, Huntington's; Chorea, Chronic Progressive Hereditary (Huntington); Huntington Disease, Late Onset; Late-Onset Huntington Disease; Huntington Disease, Late-Onset; Late Onset Huntington Disease; Juvenile Huntington Disease; Juvenile-Onset Huntington Disease; Juvenile Onset Huntington Disease; Huntington Disease, Juvenile-Onset; Huntington Disease, Juvenile Onset; Huntington Disease, Juvenile; Akinetic-Rigid Variant of Huntington Disease; Akinetic Rigid Variant of Huntington Disease; Huntington Disease, Akinetic-Rigid Variant; Huntington Disease, Akinetic Rigid Variant;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.228.140.079.545; C10.228.140.380.278; C10.228.662.262.249.750; C10.574.500.497; C16.320.400.430; F03.087.250.400; F03.087.400.390;
History Note: 2000(1963)