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Hydrazines - Diagnostic use
Research News and Information

Monday, November 23, 2009

Development of a radiolabeled probe for detecting membrane type-1 matrix metalloproteinase on malignant tumors.

29 Jun 2009 Membrane type-1 matrix metalloproteinase (MT1-MMP) expressed on the tumor cell surface activates pro-MMP-2 and pro-MMP-13 to exacerbate the malignancy, suggesting its suitability as a target molecule for diagnosis by in vivo molecular imaging. Thus, ... Read more...


Use of fluorescence indicators in receptor ligands.

30 Dec 2008 Fluorescence techniques can provide insights into the environment of fluorescent indicators incorporated within a ligand as it is bound to its receptor. Fluorescent indicators of different sizes and chemical characteristics ranging from hydrophilic ... Read more...


Breast tumor targeting with (99m)Tc-HYNIC-PR81 complex as a new biologic radiopharmaceutical.

29 Sep 2008 Human epithelial mucin, MUC1, is commonly overexpressed in adenocarcinoma that includes more than 80% of breast cancers. The PR81 is a murine anti-MUC1 monoclonal antibody (MAb) that was prepared against the human breast cancer. We developed an ... Read more...

 

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Technical information about 'Hydrazines'

Registry Number: 0

Descriptor UI: D006834

Alternative terms: Hydrazines;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.442;

Technical Notes: do not confuse with HYDRAZONES

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