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Hydrocortisone - Blood
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Definition of 'Hydrocortisone'

The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Common names: Hydrocortisone; Cortisol; Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer; Hydrocortisone, (11 alpha)-Isomer; Epicortisol; 11-Epicortisol; 11 Epicortisol; Cortifair; Cortril

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Saturday, November 21, 2009

Adrenal function testing in pediatric cancer survivors.

13 Dec 2009 BACKGROUND: Central adrenal insufficiency is observed after cranial radiation therapy for cancer. Screening at risk patients is recommended, but the best screening strategy is unknown. METHODS: A retrospective review of pediatric cancer survivors ... Read more...


Pretreatment with stress cortisol enhances the human systemic inflammatory response to bacterial endotoxin.

29 Sep 2009 OBJECTIVE: There is continuing controversy regarding the effect of glucocorticoids on a systemic inflammatory process. Based ona model of glucocorticoid action that includes both pro- and anti-inflammatory effects, we used the human experimental ... Read more...


Relative adrenal insufficiency.

29 Sep 2009 PURPOSE OF REVIEW: This article will review the clinical presentation, diagnosis, and treatment of acute adrenal insufficiency and explore the concept of 'relative adrenal insufficiency' in the critically ill. RECENT FINDINGS: Current dogma suggests ... Read more...

 

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Technical information about 'Hydrocortisone'

Definition: The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Chemical name: Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

Registry Number: 50-23-7

Descriptor UI: D006854

Alternative terms: Hydrocortisone; Cortisol; Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer; Hydrocortisone, (11 alpha)-Isomer; Epicortisol; 11-Epicortisol; 11 Epicortisol; Cortifair; Cortril;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Inflammatory Agents;

Tree Number: D04.808.745.745.654.600; D06.472.040.585.353.476; D06.472.040.585.478.392;

History Note: /adv eff-pois-tox was HYDROCORTISONE TOXICOLOGY 1963-65

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