Hydrocortisone - Metabolism
Research News and Information

Saturday, November 21, 2009

Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response.

29 Nov 2009 Following our recent findings on the presence of human cytomegalovirus (HCMV) in the normal human adrenal cortex and in adrenocortical tumors, especially in cortisol-secreting tumors, aim of the present study was to investigate the direct effects of ... Read more...

Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.

3 Oct 2009 Studies have shown that aspirin may decrease blood pressure when given at bedtime but not when administered on awakening. However, until now, a biologically plausible mechanism of this striking phenomenon was not revealed. We investigated the effect ... Read more...

Children's context inappropriate anger and salivary cortisol.

30 Aug 2009 Some children show emotion that is not consistent with normative appraisal of the context and can therefore be defined as context inappropriate (CI). The authors used individual growth curve modeling and hierarchical multiple regression analyses to ... Read more...

Latest indexed articles for 'Hydrocortisone - Metabolism'

These are the very latest articles for this heading:

• Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response. 29 Nov 2009
• Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines. 3 Oct 2009
• Children's context inappropriate anger and salivary cortisol. 30 Aug 2009
• Stress questionnaires and stress biomarkers during pregnancy. 30 Aug 2009
• Identification of two glucocorticoid response elements in the promoter region of the ubiquitous isoform of glutamine synthetase in gulf toadfish, Opsanus beta. 3 Aug 2009
• Is there a rationale for cortisol-based treatments for PTSD? 30 Jul 2009
• Is a dark virtual environment scary? 30 Jul 2009
• Cushing's syndrome of nonpituitary causes. 30 Jul 2009
• Association of daily stressors and salivary cortisol in spinal cord injury. 30 Jul 2009
• Effects of Ramadan fasting on physical performance and metabolic, hormonal, and inflammatory parameters in middle-distance runners. 30 Jul 2009
• Validation of a radioimmunoassay for measuring fecal cortisol metabolites in the hystricomorph rodent, Octodon degus. 30 Jul 2009
• A Holy Grail of clinical pharmacology: prediction of drug pharmacokinetics and pharmacodynamics in the individual patient. 30 Jul 2009
• Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory. 27 Jul 2009
• Day-to-day variation in saliva cortisol--relation with sleep, stress and self-rated health. 20 Jul 2009
• Cortisol patterns and brachial artery reactivity in a high stress environment. 15 Jul 2009
• Specificity of screening tests for Cushing's syndrome in an overweight and obese population. 12 Jul 2009
• Utility of salivary cortisol measurements in Cushing's syndrome and adrenal insufficiency. 12 Jul 2009
• Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling. 12 Jul 2009
• Long-term safety of mometasone furoate administered via a dry powder inhaler in children: Results of an open-label study comparing mometasone furoate with beclomethasone dipropionate in children with persistent asthma. 11 Jul 2009
• Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis. 5 Jul 2009

See a longer list of these articles.

Technical information about 'Hydrocortisone'

Definition: The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Chemical name: Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

Registry Number: 50-23-7

Descriptor UI: D006854

Alternative terms: Hydrocortisone; Cortisol; Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer; Hydrocortisone, (11 alpha)-Isomer; Epicortisol; 11-Epicortisol; 11 Epicortisol; Cortifair; Cortril;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Inflammatory Agents;

Tree Number: D04.808.745.745.654.600; D06.472.040.585.353.476; D06.472.040.585.478.392;

History Note: /adv eff-pois-tox was HYDROCORTISONE TOXICOLOGY 1963-65