Hydrocortisone - Research News and Information

Saturday, January 10, 2009

Bigger groups have fewer parasites and similar cortisol levels: a multi-group analysis in red colobus monkeys.

30 Oct 2008 If stress and disease impose fitness costs, and if those costs vary as a function of group size, then stress and disease should exert selection pressures on group size. We assessed the relationships between group size, stress, and parasite ... Read more...

Nitric oxide inhalation and glucocorticoids as combined treatment in human experimental endotoxemia.

30 Oct 2008 OBJECTIVE: Inhaled nitric oxide and glucocorticoids as a combination therapy may attenuate endotoxin-induced inflammatory responses in humans as indicated by levels of cytokines and clinical signs. Since other authors have shown that combined ... Read more...

In vivo exposure to high or low cortisol has biphasic effects on inflammatory response pathways of human monocytes.

30 Oct 2008 BACKGROUND: Recent studies demonstrate that glucocorticoids (GCs) have both supportive (stimulatory) and suppressive effects on immune responses, depending upon the GC concentration. Since some GC effects on inflammation are stimulatory, we ... Read more...

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Latest indexed articles for 'Hydrocortisone'

These are the very latest articles for this heading:

• Bigger groups have fewer parasites and similar cortisol levels: a multi-group analysis in red colobus monkeys. 30 Oct 2008
• Nitric oxide inhalation and glucocorticoids as combined treatment in human experimental endotoxemia. 30 Oct 2008
• In vivo exposure to high or low cortisol has biphasic effects on inflammatory response pathways of human monocytes. 30 Oct 2008
• The effects of stress and APOE genotype on cognition in older adults. 30 Oct 2008
• Do cortisol concentrations predict short-term outcomes in extremely low birth weight infants? 29 Sep 2008
• Is there a "normal" range of serum cortisol concentration for preterm infants? 29 Sep 2008
• [Dysregulation of homeostasis in severe sepsis: relevance and therapeutic options] 13 Sep 2008
• Management of adrenal insufficiency during the stress of medical illness and surgery.Comment. 13 Sep 2008
• Interleukin-6, cortisol, and depressive symptoms in ovarian cancer patients. 6 Sep 2008
• Ciproxin HC eardrops application for funding--and response from PHARMAC. 3 Sep 2008
• Direct injection LC/ESI-MS horse urine analysis for the quantification and identification of threshold substances for doping control. I. Determination of hydrocortisone. 30 Aug 2008
• The neurobiology of psychopathy. 30 Aug 2008
• Hydrocortisone in severe sepsis: time to accept the null hypothesis? 30 Aug 2008
• Strategies to screen for adrenal suppression in children with asthma: there is no consensus among UK centres. 30 Aug 2008
• Combined vs. Isoflurane/Fentanyl anesthesia for major abdominal surgery: Effects on hormones and hemodynamics. 30 Aug 2008
• Adrenal suppression following a single dose of etomidate for rapid sequence induction: a prospective randomized study. 30 Aug 2008
• A case of Legionella pneumophila pneumonia followed by invasive aspergillosis. 30 Aug 2008
• [ACTH therapy for infantile spasms with chronic renal failure] 30 Aug 2008
• Reconstructed epidermis and full-thickness skin for absorption testing: influence of the vehicles used on steroid permeation. 30 Aug 2008
• Best evidence in critical care medicine. Steroids in sepsis: bulking up the evidence. 30 Aug 2008

See a longer list of these articles.

Technical information about 'Hydrocortisone'

Definition: The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Chemical name: Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

Registry Number: 50-23-7

Descriptor UI: D006854

Alternative terms: Hydrocortisone; Cortisol; Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer; Hydrocortisone, (11 alpha)-Isomer; Epicortisol; 11-Epicortisol; 11 Epicortisol; Cortifair; Cortril;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Inflammatory Agents;

Tree Number: D04.808.745.745.654.600; D06.472.040.585.353.476; D06.472.040.585.478.392;

History Note: /adv eff-pois-tox was HYDROCORTISONE TOXICOLOGY 1963-65