Hydrocortisone
Research News and Information

Saturday, November 21, 2009

Increased vulnerability of the spinal cord to radiation or intrathecal chemotherapy during adolescence: A report from the Children's Oncology Group.

13 Dec 2009 PURPOSE: To assess the rate of spinal cord toxicity in adolescents resulting from chemoradiotherapy of parameningeal sarcoma. METHODS AND MATERIALS: Of 152 patients with parameningeal sarcoma treated per the Intergroup Rhabdomyosarcoma Study Group ... Read more...

Adrenal function testing in pediatric cancer survivors.

13 Dec 2009 BACKGROUND: Central adrenal insufficiency is observed after cranial radiation therapy for cancer. Screening at risk patients is recommended, but the best screening strategy is unknown. METHODS: A retrospective review of pediatric cancer survivors ... Read more...

Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response.

29 Nov 2009 Following our recent findings on the presence of human cytomegalovirus (HCMV) in the normal human adrenal cortex and in adrenocortical tumors, especially in cortisol-secreting tumors, aim of the present study was to investigate the direct effects of ... Read more...

Latest indexed articles for 'Hydrocortisone'

These are the very latest articles for this heading:

• Increased vulnerability of the spinal cord to radiation or intrathecal chemotherapy during adolescence: A report from the Children's Oncology Group. 13 Dec 2009
• Adrenal function testing in pediatric cancer survivors. 13 Dec 2009
• Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response. 29 Nov 2009
• Severe hyponatremia with high urine sodium and osmolality. 30 Oct 2009
• Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines. 3 Oct 2009
• Cold pressor stress impairs performance on working memory tasks requiring executive functions in healthy young men. 29 Sep 2009
• Pretreatment with stress cortisol enhances the human systemic inflammatory response to bacterial endotoxin. 29 Sep 2009
• Relative adrenal insufficiency. 29 Sep 2009
• Physiological and psychological effects of escape from a sunken submarine on shore and at sea. 29 Sep 2009
• [Ears "made of stone" - unusual secondary phenomenon of undersubstituted adrenal insufficiency] 8 Sep 2009
• The acute response of plasma brain-derived neurotrophic factor as a result of exercise in major depressive disorder. Sep 2009
• Late-night and low-dose dexamethasone-suppressed cortisol in saliva and serum for the diagnosis of cortisol-secreting adrenal adenomas. 31 Aug 2009
• Children's context inappropriate anger and salivary cortisol. 30 Aug 2009
• ["Many help many"--better compliance?] 30 Aug 2009
• Hydrocortisone suppression of the expression of VEGF may relate to toll-like receptor (TLR) 2 and 4. 30 Aug 2009
• Stress questionnaires and stress biomarkers during pregnancy. 30 Aug 2009
• Effects of budesonide inhalation on energy expenditure, somatic growth and salivary cortisol levels in preterm infants with chronic lung disease. 30 Aug 2009
• Salivary steroids. 30 Aug 2009
• Elevations in sex hormones in dogs with sudden acquired retinal degeneration syndrome (SARDS). 30 Aug 2009
• The context counts: congruent learning and testing environments prevent memory retrieval impairment following stress. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Hydrocortisone'

Definition: The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Chemical name: Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

Registry Number: 50-23-7

Descriptor UI: D006854

Alternative terms: Hydrocortisone; Cortisol; Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer; Hydrocortisone, (11 alpha)-Isomer; Epicortisol; 11-Epicortisol; 11 Epicortisol; Cortifair; Cortril;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Inflammatory Agents;

Tree Number: D04.808.745.745.654.600; D06.472.040.585.353.476; D06.472.040.585.478.392;

History Note: /adv eff-pois-tox was HYDROCORTISONE TOXICOLOGY 1963-65