Hydrogen Peroxide - Pharmacology
Research News and Information

Monday, November 23, 2009

Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations.

12 Oct 2009 In Alzheimer's disease (AD), rod-like cofilin aggregates (cofilin-actin rods) and thread-like inclusions containing phosphorylated microtubule-associated protein (pMAP) tau form in the brain (neuropil threads), and the extent of their presence ... Read more...

Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.

29 Sep 2009 The enhanced oxidative stress associated with type 2 diabetes mellitus contributes to disease pathogenesis. We previously identified plasma membrane-associated ATP-sensitive K+ (KATP) channels of pancreatic beta cells as targets for oxidants. Here, ... Read more...

Combination treatment of hydrogen peroxide and X-rays induces apoptosis in human prostate cancer PC-3 cells.

29 Sep 2009 PURPOSE: To study the effect of hydrogen peroxide (H(2)O(2)) on radiation-induced apoptosis in human prostate cancer PC-3 cells. METHODS AND MATERIALS: At 4h before the irradiation, PC-3 cells were exposed to 10mM ammonium chloride (NH(4)Cl) ... Read more...

Latest indexed articles for 'Hydrogen Peroxide - Pharmacology'

These are the very latest articles for this heading:

• Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations. 12 Oct 2009
• Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. 29 Sep 2009
• Combination treatment of hydrogen peroxide and X-rays induces apoptosis in human prostate cancer PC-3 cells. 29 Sep 2009
• Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells. 23 Sep 2009
• Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions. 23 Sep 2009
• Inositol pyrophosphates modulate hydrogen peroxide signalling. 12 Sep 2009
• Creatine supplementation prevents the inhibition of myogenic differentiation in oxidatively injured C2C12 murine myoblasts. 30 Aug 2009
• The OsDHODH1 gene is involved in salt and drought tolerance in rice. 30 Aug 2009
• The Legionella pneumophila Dps homolog is regulated by iron and involved in multiple stress tolerance. 30 Aug 2009
• Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants. 30 Aug 2009
• Oxidative stress induces anti-hepatitis C virus status via the activation of extracellular signal-regulated kinase. 30 Aug 2009
• The selenoproteome is dispensable in bloodstream forms of Trypanosoma brucei. 29 Aug 2009
• Anti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage. 29 Aug 2009
• Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells. 27 Aug 2009
• Adaptation of neuronal cells to chronic oxidative stress is associated with altered cholesterol and sphingolipid homeostasis and lysosomal function. 25 Aug 2009
• A slowly inactivating sodium current contributes to spontaneous diastolic depolarization of atrial myocytes. 19 Aug 2009
• Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin. 16 Aug 2009
• Protein phosphatase 5 protects neurons against amyloid-beta toxicity. 15 Aug 2009
• Characterization of hydrogen peroxide-induced DNA release by Streptococcus sanguinis and Streptococcus gordonii. 12 Aug 2009
• Cytoprotection against hydrogen peroxide-induced cell death in cultured mouse mesangial cells by erigeroflavanone, a novel compound from the flowers of Erigeron annuus. 12 Aug 2009

See a longer list of these articles.

Technical information about 'Hydrogen Peroxide'

Definition: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.

Chemical name: Hydrogen peroxide (H2O2)

Registry Number: 7722-84-1

Descriptor UI: D006861

Alternative terms: Hydrogen Peroxide; Peroxide, Hydrogen; Hydrogen Peroxide (H2O2); Hydroperoxide; Superoxol; Oxydol; Perhydrol;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Infective Agents, Local; Oxidants;

Tree Number: D01.248.497.158.685.750.424; D01.339.431.374.424; D01.650.550.750.400;