Hydrophobicity
Research News and Information

Friday, March 12, 2010

Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae.

9 Dec 2009 The Saccharomyces cerevisiae genome encodes a Flo (flocculin) adhesin family responsible for cell-cell and cell-surface adherence. In commonly used laboratory strains, these FLO genes are transcriptionally silent, because of a nonsense mutation in ... Read more...

Role of hydrophobic and electrostatic interactions in coiled coil stability and specificity.

Nov 2009 We have screened two coiled coil-forming libraries in which core a and electrostatic e/g positions have been partially randomized. We observed the relative ability of these residues to confer coiled coil stability using a protein-fragment ... Read more...

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain.

16 Oct 2009 Heat shock protein 90 (Hsp90) is an essential molecular chaperone in eukaryotes, as it regulates diverse signal transduction nodes that integrate numerous environmental cues to maintain cellular homeostasis. Hsp90 also is secreted from normal and ... Read more...

Latest indexed articles for 'Hydrophobicity'

These are the very latest articles for this heading:

• Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae. 9 Dec 2009
• Role of hydrophobic and electrostatic interactions in coiled coil stability and specificity. Nov 2009
• Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. 16 Oct 2009
• GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. 14 Oct 2009
• A solid-state deuterium NMR and sum-frequency generation study of the side-chain dynamics of peptides adsorbed onto surfaces. 12 Oct 2009
• Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner. 10 Oct 2009
• Molecular dynamics study of non-nucleoside reverse transcriptase inhibitor 4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile (TMC278/rilpivirine) aggregates: correlation between amphiphilic properties of the drug and oral bioavailability. 6 Oct 2009
• Prediction of protein-glucose binding sites using support vector machines. 29 Sep 2009
• Dissecting membrane protein architecture: An annotation of structural complexity. 29 Sep 2009
• De novo molecular modeling and biophysical characterization of Manduca sexta eclosion hormone. 27 Sep 2009
• Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. 23 Sep 2009
• Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. 20 Sep 2009
• Induced beta-barrel formation of the Alzheimer's Abeta25-35 oligomers on carbon nanotube surfaces: implication for amyloid fibril inhibition. 14 Sep 2009
• How does a simplified-sequence protein fold? 14 Sep 2009
• The structure of neuroglobin at high Xe and Kr pressure reveals partial conservation of globin internal cavities. 14 Sep 2009
• Structural and functional constraints in the evolution of protein families. 14 Sep 2009
• Polymer-water partition coefficients of hydrophobic compounds for passive sampling: application of cosolvent models for validation. 13 Sep 2009
• A novel model and experimental analysis of hydrophilic and hydrophobic agent release from biodegradable polymers. 13 Sep 2009
• Probing the allosteric modulator binding site of GluR2 with thiazide derivatives. 13 Sep 2009
• Activation of membrane cholesterol by 63 amphipaths. 13 Sep 2009

See a longer list of these articles.

Technical information about 'Hydrophobicity'

Definition: The property of substances of reduced affinity for or repulsion of water.

Descriptor UI: D027141

Alternative terms: Hydrophobicity; Hydrophobic Surfaces; Hydrophobic Interactions; Hydrophobic Interaction; Interaction, Hydrophobic; Interactions, Hydrophobic;

Tree Number: G02.842.540;

History Note: 2002

Technical Notes: do not confuse with HYDROPHOBIA see RABIES