Hydroxocobalamin - Therapeutic use
Research News and Information

Thursday, March 18, 2010

Oral manifestations of vitamin B12 deficiency: a case report.

30 Aug 2009 Megaloblastic anemias are a subgroup of macrocytic anemias, in which distinctive morphologic abnormalities occur in red cell precursors in bone marrow, namely megaloblastic erythropoiesis. Of the many causes of megaloblastic anemia, the most common ... Read more...

A case report of pernicious anemia and recurrent aphthous stomatitis.

27 Feb 2009 AIM: The aim of this report is to present the management of a patient with pernicious anemia afflicted with recurrent aphthous stomatitis (RAS). BACKGROUND: RAS is one of the most common lesions of the oral mucosa. Although the exact etiology of RAS ... Read more...

Laboratory interferences with the newer cyanide antidote: hydroxocobalamin.

30 Jan 2009 Cyanide poisoning occurs in many smoke inhalation victims. The newest FDA-approved treatment for acute cyanide intoxication is hydroxocobalamin (Cyanokit). However, hydroxocobalamin exhibits chemical properties that can disrupt several clinical ... Read more...

Latest indexed articles for 'Hydroxocobalamin - Therapeutic use'

These are the very latest articles for this heading:

• Cyanide poisoning in Taiwan. Oct 2009
• Oral manifestations of vitamin B12 deficiency: a case report. 30 Aug 2009
• A case report of pernicious anemia and recurrent aphthous stomatitis. 27 Feb 2009
• Laboratory interferences with the newer cyanide antidote: hydroxocobalamin. 30 Jan 2009
• Hydroxocobalamin: a better cyanide antidote. 30 Oct 2008
• [Availability of hydroxicobalamin as an antidote for patients intoxicated by fire smoke in Spanish hospitals] 11 Sep 2008
• Diagnostic work-up and management of patients with isolated methylmalonic acidurias in European metabolic centres. 25 May 2008
• Role of hydroxocobalamin in acute cyanide poisoning. 6 Apr 2008
• Hydroxocobalamin versus thiosulfate for cyanide poisoning. 28 Feb 2008
• Reply to: "Is hydroxocobalamin safe and effective for smoke inhalation? Searching for guidance in the haze". 30 Dec 2007
• Hydroxocobalamin for acute cyanide poisoning in smoke inhalation. 30 Dec 2007
• [A rare inborn error of intracellular processing of cobalamine presenting with microcephalus and megaloblastic anemia: a report of 3 children] 30 Oct 2007
• Interference of the cyanide antidote hydroxocobalamin with carboxyhemoglobin measurements should not limit clinical use in suspected or confirmed cyanide poisoning. 30 Oct 2007
• A novel paradigm for assessing efficacies of potential antidotes against neurotoxins in mice. 8 Oct 2007
• Prevention of hydrogen sulfide (H2S)-induced mouse lethality and cytotoxicity by hydroxocobalamin (vitamin B(12a)). 13 Sep 2007
• Hemolytic uremic syndrome (HUS) secondary to cobalamin C (cblC) disorder. 12 Sep 2007
• [Floppy baby with macrocytic anemia and vegan mother] 27 Aug 2007
• Enhancing public health preparedness for a terrorist attack involving cyanide. 27 Aug 2007
• Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. 30 May 2007
• Is hydroxocobalamin safe and effective for smoke inhalation? Searching for guidance in the haze. 30 May 2007

See a longer list of these articles.

Technical information about 'Hydroxocobalamin'

Definition: Injectable form of VITAMIN B 12 that has been used therapeutically to treat VITAMIN B 12 DEFICIENCY.

Chemical name: Cobinamide, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole

Registry Number: 13422-51-0

Descriptor UI: D006879

Alternative terms: Hydroxocobalamin; Hydroxo-Cobalamin; Hydroxycobalamin;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Vitamin B Complex; Hematinics;

Tree Number: D03.383.129.578.840.437.777.560; D03.549.909.437.777.560; D04.345.783.437.777.560;