Hypericum
Research News and Information

Sunday, November 22, 2009

p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death.

29 Nov 2009 Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein ... Read more...

In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey.

29 Sep 2009 Hypericum perforatum (St. John's wort) is well-established for its antidepressant activity throughout the world and also various other species within this genus are used in different folk medicines. Hyperforin of St. John's wort inhibited growth of ... Read more...

Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum.

12 Aug 2009 A spectrum of eight pharmacologically important secondary compounds, all putatively belonging to the polyketide pathway (hypericin, pseudohypericin, emodin, hyperforin, hyperoside, rutin, quercetin, and quercitrin) were analyzed in several ... Read more...

Latest indexed articles for 'Hypericum'

These are the very latest articles for this heading:

• p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death. 29 Nov 2009
• Contraception for women. First consultation for the pill. 3 Oct 2009
• In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey. 29 Sep 2009
• Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum. 12 Aug 2009
• Quinones as key intermediates in natural products Synthesis. Syntheses of bioactive xanthones from Hypericum perforatum. Aug 2009
• Kava and St. John's Wort: current evidence for use in mood and anxiety disorders. 30 Jul 2009
• Acylphloroglucinol, biyouyanagiol, biyouyanagin B, and related spiro-lactones from Hypericum chinense. 30 Jul 2009
• Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver. 30 Jul 2009
• St. John's Wort inhibits adipocyte differentiation and induces insulin resistance in adipocytes. 28 Jul 2009
• Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum. 11 Jul 2009
• Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo. 3 Jul 2009
• LC-MS and LC-PDA analysis of Hypericum empetrifolium and Hypericum sinaicum. 29 Jun 2009
• Predictors of placebo response in a randomized, controlled trial of phytotherapy in menopause. 29 Jun 2009
• [Interaction between Saint Johns Wort and alcohol deterrents?] 29 Jun 2009
• Effects of St. John's wort extract on indinavir pharmacokinetics in rats: differentiation of intestinal and hepatic impacts. 22 Jun 2009
• Are we drawing the right conclusions from randomised placebo-controlled trials? A post-hoc analysis of data from a randomised controlled trial. 21 Jun 2009
• Use of an injection port for thermochemolysis-gas chromatography/mass spectrometry: rapid profiling of biomaterials. 8 Jun 2009
• [Ligans from branch of Hypericum petiolulatum] 30 May 2009
• Evidence for phosphatase activity of p27SJ and its impact on the cell cycle. 30 May 2009
• Hypericum perforatum extracts healed gastric lesions induced by hypothermic restraint stress in Wistar rats. 30 May 2009

See a longer list of these articles.

Technical information about 'Hypericum'

Definition: Genus of perennial plants in the family CLUSIACEAE (sometimes classified as Hypericaceae). Herbal and homeopathic preparations are used for depression, neuralgias, and a variety of other conditions. Hypericum contains flavonoids; GLYCOSIDES; mucilage, TANNINS; volatile oils (OILS, ESSENTIAL), hypericin and hyperforin.

Descriptor UI: D020902

Alternative terms: Hypericum; Hypericum perforatum; Saint Johns Wort; St. Johnswort; St. John's Wort; St. Johns Wort; Saint John's Wort; Saint Johnswort;

Allowable Qualifiers: adverse effects; anatomy & histology; classification; cytology; drug effects; embryology; enzymology; genetics; growth & development; immunology; metabolism; microbiology; parasitology; physiology; poisoning; radiation effects; toxicity; ultrastructure; chemistry; virology;

Tree Number: B06.388.100.928.249.500;

History Note: 2000; for Hypericum & St. Johns Wort use THEALES 1999

Technical Notes: coordinate with specific PLANT COMPONENTS term if pertinent; for use in therapy coordinate IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATION or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manual 26.29