Hypericum - Research News and Information

Saturday, January 10, 2009

Pseudohypericin is necessary for the light-activated inhibition of prostaglandin E2 pathways by a 4 component system mimicking an Hypericum perforatum fraction.

13 Aug 2008 Hypericum perforatum (Hp) has been used medicinally to treat a variety of conditions including mild-to-moderate depression. Recently, several anti-inflammatory activities of Hp have been reported. An ethanol extract of Hp was fractionated with the ... Read more...

Signal interaction between nitric oxide and hydrogen peroxide in heat shock-induced hypericin production of Hypericum perforatum suspension cells.

Aug 2008 Heat shock (HS, 40 degrees C, 10 min) induces hypericin production, nitric oxide (NO) generation, and hydrogen peroxide (H(2)O(2)) accumulation of Hypericum perforatum suspension cells. Catalase (CAT) and NO specific scavenger ... Read more...

An Iranian herbal-marine medicine, MS14, ameliorates experimental allergic encephalomyelitis.

30 Jul 2008 Multiple sclerosis is an inflammatory and demyelinating disease of the central nervous system which mainly affects young adults. To overcome wide spectrum troublesome symptoms of multiple sclerosis which affects the quality of life both in patients ... Read more...

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Latest indexed articles for 'Hypericum'

These are the very latest articles for this heading:

• Pseudohypericin is necessary for the light-activated inhibition of prostaglandin E2 pathways by a 4 component system mimicking an Hypericum perforatum fraction. 13 Aug 2008
• Signal interaction between nitric oxide and hydrogen peroxide in heat shock-induced hypericin production of Hypericum perforatum suspension cells. Aug 2008
• An Iranian herbal-marine medicine, MS14, ameliorates experimental allergic encephalomyelitis. 30 Jul 2008
• Prenylated Phloroglucinol Derivatives from Hypericum perforatum var. angustifolium. 30 Jul 2008
• Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof. 21 Jul 2008
• Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins. 19 Jul 2008
• Clinically relevant safety issues associated with St. John's wort product labels. 15 Jul 2008
• Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea. 29 Jun 2008
• Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics. 29 Jun 2008
• Complementary medicine for psychiatric disorders in children and adolescents. 29 Jun 2008
• Bioactive constituent production in St. John's Wort in vitro hairy roots. Regenerated plant lines. 12 Jun 2008
• Tomoeones A-H, cytotoxic phloroglucinol derivatives from Hypericum ascyron. 11 Jun 2008
• Hypericum perforatum (St John's wort) for attention-deficit/hyperactivity disorder in children and adolescents: a randomized controlled trial. 9 Jun 2008
• Quality of efficacy research in complementary and alternative medicine. 9 Jun 2008
• Antiinflammatory and antioxidant activity of Hypericum rumeliacum Boiss. subsp. apollinis (Boiss. & Heldr.) Robson & Strid methanol extract. 30 May 2008
• Editorial: in this issue. 30 May 2008
• An update on clinical drug interactions with the herbal antidepressant St. John's wort. 30 May 2008
• Free amino acids in botanicals and botanical preparations. 30 May 2008
• Characterizing the metabolic fingerprint and anti-inflammatory activity of Hypericum gentianoides. 29 May 2008
• Phloroglucinols with antioxidant activity and xanthonolignoids from the heartwood of Hypericum geminiflorum. 29 May 2008

See a longer list of these articles.

Technical information about 'Hypericum'

Definition: Genus of perennial plants in the family CLUSIACEAE (sometimes classified as Hypericaceae). Herbal and homeopathic preparations are used for depression, neuralgias, and a variety of other conditions. Hypericum contains flavonoids; GLYCOSIDES; mucilage, TANNINS; volatile oils (OILS, ESSENTIAL), hypericin and hyperforin.

Descriptor UI: D020902

Alternative terms: Hypericum; Hypericum perforatum; Saint Johns Wort; St. Johnswort; St. John's Wort; St. Johns Wort; Saint John's Wort; Saint Johnswort;

Allowable Qualifiers: adverse effects; anatomy & histology; classification; cytology; drug effects; embryology; enzymology; genetics; growth & development; immunology; metabolism; microbiology; parasitology; physiology; poisoning; radiation effects; toxicity; ultrastructure; chemistry; virology;

Tree Number: B06.388.100.928.249.500;

History Note: 2000; for Hypericum & St. Johns Wort use THEALES 1999

Technical Notes: coordinate with specific PLANT COMPONENTS term if pertinent; for use in therapy coordinate IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATION or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manual 26.29