Hypersensitivity, Delayed - Immunology
Research News and Information

Saturday, November 21, 2009

Regions of differences encoded antigens as targets for immunodiagnosis of tuberculosis in humans.

29 Sep 2009 Tuberculosis is one of the major global health problems causing nearly 2 million deaths every year. It continues to be a leading cause of morbidity and mortality in developing countries. Accurate early diagnosis and proper treatment can control the ... Read more...

Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys.

29 Sep 2009 Blockade of co-stimulation signals between T cells and antigen-presenting cells could be an important approach for treatment of autoimmune diseases and transplant rejection. Recently a series of small compound inhibitors which bind human CD80 (B7-1) ... Read more...

Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice.

19 Aug 2009 In mice and humans, the immunologic effects of developmental exposure to noninherited maternal antigens (NIMAs) are quite variable. This heterogeneity likely reflects differences in the relative levels of NIMA-specific T regulatory (T(R)) versus T ... Read more...

Latest indexed articles for 'Hypersensitivity, Delayed - Immunology'

These are the very latest articles for this heading:

• Regions of differences encoded antigens as targets for immunodiagnosis of tuberculosis in humans. 29 Sep 2009
• Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys. 29 Sep 2009
• Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice. 19 Aug 2009
• Molecular mechanisms of leukocyte trafficking in T-cell-mediated skin inflammation: insights from intravital imaging. 18 Aug 2009
• Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging. 8 Aug 2009
• Novel immunoadjuvants based on cationic lipid: Preparation, characterization and activity in vivo. 3 Aug 2009
• Rapid desensitization for hypersensitivity reactions to medications. 30 Jul 2009
• In vitro tests in drug hypersensitivity diagnosis. 30 Jul 2009
• Skin testing in delayed reactions to drugs. 30 Jul 2009
• Heparin allergy: delayed-type non-IgE-mediated allergic hypersensitivity to subcutaneous heparin injection. 30 Jul 2009
• Immediate and delayed reactions to radiocontrast media: is there an allergic mechanism? 30 Jul 2009
• Protective effect of a synapsin peptide genetically fused to the B subunit of Escherichia coli heat-labile enterotoxin in rat autoimmune encephalomyelitis. 30 Jul 2009
• Decreased risk for atopic disorder associated with highly hyperreactive tuberculin skin test reaction in children and adolescents. 29 Jun 2009
• Immunomodulatory activity of Zingiber officinale Roscoe, Salvia officinalis L. and Syzygium aromaticum L. essential oils: evidence for humor- and cell-mediated responses. 29 Jun 2009
• Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to sheep RBC and chicken ovalbumin. 29 Jun 2009
• Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation. 20 Jun 2009
• The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity. 13 Jun 2009
• The effect of selenium supplementation on DTH skin responses in healthy North American men. 10 Jun 2009
• Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9. 7 Jun 2009
• Partial role of TLR4 as a receptor responding to damage-associated molecular pattern. 4 Jun 2009

See a longer list of these articles.

Technical information about 'Hypersensitivity, Delayed'

Definition: An increased reactivity to specific antigens mediated not by antibodies but by cells.

Descriptor UI: D006968

Alternative terms: Hypersensitivity, Delayed; Hypersensitivity, Type IV; Hypersensitivities, Type IV; Type IV Hypersensitivities; Delayed Hypersensitivity; Delayed Hypersensitivities; Hypersensitivities, Delayed; Type IV Hypersensitivity; Hypersensitivity, Tuberculin-Type; Hypersensitivities, Tuberculin-Type; Hypersensitivity, Tuberculin Type; Tuberculin-Type Hypersensitivities; Tuberculin-Type Hypersensitivity; Tuberculin Type Hypersensitivity;

Related Mesh Headings: Cell Migration Inhibition; Encephalomyelitis, Acute Disseminated;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C20.543.418;

History Note: 66(65)

Technical Notes: IM; use qualif with caution; /chem ind: coord IM with DRUG HYPERSENSITIVITY or specifics (IM)