Hypersensitivity, Delayed - Pathology
Research News and Information

Monday, November 23, 2009

Rapid desensitization for hypersensitivity reactions to medications.

30 Jul 2009 Drug desensitization is the induction of temporary clinical unresponsiveness to drug antigens to which patients have presented severe hypersensitivity reactions. It is typically achieved by gradual reintroduction of small doses of drug antigens at ... Read more...

In vitro tests in drug hypersensitivity diagnosis.

30 Jul 2009 The diagnosis of a drug hypersensitivity reaction (DHR) is a challenging task because multiple and complex mechanisms are involved. Better understanding of immunologic pathomechanisms in DHRs and rapid progress in cellular-based in-vitro tests can ... Read more...

Tuberculin sensitivity and morphological immune response in guinea pigs after application of minimal sensitizing dose of BCG vaccine, substrain Sofia SL222.

20 Apr 2009 During the investigation of the BCG allergenic potency it is advisable to vaccinate with decreasing doses, estimating the lowest dose that induces tuberculin sensitivity and specific morphological inflammation. Although the biological test does not ... Read more...

Latest indexed articles for 'Hypersensitivity, Delayed - Pathology'

These are the very latest articles for this heading:

• Rapid desensitization for hypersensitivity reactions to medications. 30 Jul 2009
• In vitro tests in drug hypersensitivity diagnosis. 30 Jul 2009
• Tuberculin sensitivity and morphological immune response in guinea pigs after application of minimal sensitizing dose of BCG vaccine, substrain Sofia SL222. 20 Apr 2009
• Role of the heparan sulfate proteoglycan syndecan-1 (CD138) in delayed-type hypersensitivity. 13 Apr 2009
• Very late delayed-allergic reaction to natalizumab not associated with neutralizing antibodies. 30 Mar 2009
• A case of delayed-type hypersensitivity to subcutaneously administered drugs during anticancer immunotherapy. 7 Mar 2009
• The role of haptic macrophages in regulation of idiosyncratic drug reactions. 24 Jan 2009
• The suppression of hypersensitivity by ocular-induced CD8(+) T cells requires compatibility in the Qa-1 haplotype. 11 Jan 2009
• Metal allergic reaction in chronic refractory in-stent restenosis. 30 Dec 2008
• Trehalose dimycolate elicits eosinophilic skin hypersensitivity in mycobacteria-infected guinea pigs. 13 Dec 2008
• Immunohistological analysis of peptide-induced delayed-type hypersensitivity in advanced melanoma patients treated with melanoma antigen-pulsed mature monocyte-derived dendritic cell vaccination. 17 Sep 2008
• Doxycycline induces membrane expression of VE-cadherin on endothelial cells and prevents vascular hyperpermeability. 5 Jul 2008
• Delayed reaction after an octopus bite showing a giant cell-rich granulomatous dermatitis/panniculitis. 7 Jun 2008
• Type III systemic allergic reaction to natalizumab. 30 May 2008
• Langerhans cells are not required for efficient skin graft rejection. 11 Mar 2008
• Monitoring non-immediate allergic reactions to iodine contrast media. 10 Mar 2008
• The histological diagnosis of leprosy type 1 reactions: identification of key variables and an analysis of the process of histological diagnosis. 4 Mar 2008
• Prime-boost immunization with cruzipain co-administered with MALP-2 triggers a protective immune response able to decrease parasite burden and tissue injury in an experimental Trypanosoma cruzi infection model. 20 Feb 2008
• Sex-specific effects of glucose deprivation on cell-mediated immunity and reproduction in Siberian hamsters (Phodopus sungorus). 13 Feb 2008
• Delayed immune-mediated adverse effects related to hyaluronic acid and acrylic hydrogel dermal fillers: clinical findings, long-term follow-up and review of the literature. 30 Jan 2008

See a longer list of these articles.

Technical information about 'Hypersensitivity, Delayed'

Definition: An increased reactivity to specific antigens mediated not by antibodies but by cells.

Descriptor UI: D006968

Alternative terms: Hypersensitivity, Delayed; Hypersensitivity, Type IV; Hypersensitivities, Type IV; Type IV Hypersensitivities; Delayed Hypersensitivity; Delayed Hypersensitivities; Hypersensitivities, Delayed; Type IV Hypersensitivity; Hypersensitivity, Tuberculin-Type; Hypersensitivities, Tuberculin-Type; Hypersensitivity, Tuberculin Type; Tuberculin-Type Hypersensitivities; Tuberculin-Type Hypersensitivity; Tuberculin Type Hypersensitivity;

Related Mesh Headings: Cell Migration Inhibition; Encephalomyelitis, Acute Disseminated;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C20.543.418;

History Note: 66(65)

Technical Notes: IM; use qualif with caution; /chem ind: coord IM with DRUG HYPERSENSITIVITY or specifics (IM)