Hypersensitivity, Delayed - Therapy
Research News and Information

Sunday, November 22, 2009

Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys.

29 Sep 2009 Blockade of co-stimulation signals between T cells and antigen-presenting cells could be an important approach for treatment of autoimmune diseases and transplant rejection. Recently a series of small compound inhibitors which bind human CD80 (B7-1) ... Read more...

Rapid desensitization for hypersensitivity reactions to medications.

30 Jul 2009 Drug desensitization is the induction of temporary clinical unresponsiveness to drug antigens to which patients have presented severe hypersensitivity reactions. It is typically achieved by gradual reintroduction of small doses of drug antigens at ... Read more...

Approach to the patient with drug allergy.

30 Jul 2009 Drug allergies are adverse drug reactions mediated by the specific immune system. Despite characteristic signs (eg, skin rash) that raise awareness for possible drug allergies, they are great imitators of disease and may hide behind unexpected ... Read more...

Latest indexed articles for 'Hypersensitivity, Delayed - Therapy'

These are the very latest articles for this heading:

• Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys. 29 Sep 2009
• Rapid desensitization for hypersensitivity reactions to medications. 30 Jul 2009
• Approach to the patient with drug allergy. 30 Jul 2009
• Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models. 30 Jan 2009
• The suppression of hypersensitivity by ocular-induced CD8(+) T cells requires compatibility in the Qa-1 haplotype. 11 Jan 2009
• High-dose chemotherapy and adoptive immunotherapy in the treatment of recurrent pediatric brain tumors. 5 Nov 2008
• IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells. 30 May 2008
• Induction of regulatory dendritic cells by topical application of NF-kappaB decoy oligodeoxynucleotides. 18 May 2008
• Nickel allergy and orthodontics, a review and report of two cases. 20 Mar 2008
• Immediate and delayed hypersensitivity to latex in a social caregiver. 30 Dec 2007
• Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express IL-4. 13 Aug 2007
• A bright red pruritic rash on the forearms. 30 Jul 2007
• Management and preparedness for infusion and hypersensitivity reactions. 29 Apr 2007
• Management of cutaneous type IV hypersensitivity reactions induced by heparin. 30 Oct 2006
• Periprosthetic osteolysis: an immunologist's update. 30 Dec 2005
• [Food intolerance and allergy in the irritable bowel syndrome] 30 Aug 2005
• The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance. 7 May 2005
• Efficacy and safety of specific immunotherapy to mosquito bites. 30 Mar 2004
• Allergen specific immunotherapy attenuates early and late phase reactions in lower airways of birch pollen asthmatic patients: a double blind placebo-controlled study. 30 Dec 2003
• IL-4 from Th2-type cells suppresses induction of delayed-type hypersensitivity elicited shortly after immunization. 29 Nov 2003

See a longer list of these articles.

Technical information about 'Hypersensitivity, Delayed'

Definition: An increased reactivity to specific antigens mediated not by antibodies but by cells.

Descriptor UI: D006968

Alternative terms: Hypersensitivity, Delayed; Hypersensitivity, Type IV; Hypersensitivities, Type IV; Type IV Hypersensitivities; Delayed Hypersensitivity; Delayed Hypersensitivities; Hypersensitivities, Delayed; Type IV Hypersensitivity; Hypersensitivity, Tuberculin-Type; Hypersensitivities, Tuberculin-Type; Hypersensitivity, Tuberculin Type; Tuberculin-Type Hypersensitivities; Tuberculin-Type Hypersensitivity; Tuberculin Type Hypersensitivity;

Related Mesh Headings: Cell Migration Inhibition; Encephalomyelitis, Acute Disseminated;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C20.543.418;

History Note: 66(65)

Technical Notes: IM; use qualif with caution; /chem ind: coord IM with DRUG HYPERSENSITIVITY or specifics (IM)