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Hypothalamo-Hypophyseal System - Physiopathology
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Definition of 'Hypothalamo-Hypophyseal System'

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

Common names: Hypothalamo-Hypophyseal System; Hypothalamo Hypophyseal System; Hypothalamic-Pituitary Unit; Hypothalamic Pituitary Unit

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Sunday, November 22, 2009

Adrenal function testing in pediatric cancer survivors.

13 Dec 2009 BACKGROUND: Central adrenal insufficiency is observed after cranial radiation therapy for cancer. Screening at risk patients is recommended, but the best screening strategy is unknown. METHODS: A retrospective review of pediatric cancer survivors ... Read more...


Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli.

12 Oct 2009 Systemic injection of lipopolysaccharide (LPS) is a widely used model of immune/inflammatory challenge, which can invoke a host of CNS responses, including activation of the hypothalamic-pituitary-adrenal (HPA) axis. Inducible vascular prostaglandin ... Read more...


Stress and obesity: the role of the hypothalamic-pituitary-adrenal axis in metabolic disease.

29 Sep 2009 PURPOSE OF REVIEW: Chronic stress, combined with positive energy balance, may be a contributor to the increased risk for obesity, especially upper body obesity, and other metabolic diseases. This association may be mediated by alterations in the ... Read more...

 

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Technical information about 'Hypothalamo-Hypophyseal System'

Definition: A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

Descriptor UI: D007030

Alternative terms: Hypothalamo-Hypophyseal System; Hypothalamo Hypophyseal System; Hypothalamic-Pituitary Unit; Hypothalamic Pituitary Unit;

Related Mesh Headings: Pituitary Hormone-Releasing Hormones;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A06.688.357; A08.186.211.730.317.357.352.435; A08.713.357;

History Note: 65

Technical Notes: hypothalamo-pituitary-adrenal axis: coordinate HYPOTHALAMO-HYPOPHYSEAL SYSTEM + PITUITARY-ADRENAL SYSTEM; emphasis here is on interrelation between hypothalamus & pituitary: do not use as a substitute for HYPOTHALAMUS & PITUITARY GLAND as entities; diseases: coordinate IM with HYPOTHALAMIC DISEASES (IM)

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