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Hypothalamo-Hypophyseal System - Research News and Information

Saturday, January 10, 2009

Definition of 'Hypothalamo-Hypophyseal System'

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

Common names: Hypothalamo-Hypophyseal System; Hypothalamo Hypophyseal System; Hypothalamic-Pituitary Unit; Hypothalamic Pituitary Unit

More technical Information...

Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response.

15 Oct 2008 While the hypothalamo-pituitary-adrenal axis (HPA) activates a general stress response by increasing glucocorticoid (Gc) synthesis, biological stress resulting from infections triggers the inflammatory response through production of cytokines. The ... Read more...


Hypothalamic-pituitary-adrenal axis disregulation in PrPC-null mice.

6 Oct 2008 As manifestations of prion diseases include disturbances of hypothalamic and pituitary functions, we tested the hypothesis that the cellular prion protein (PrPC) has a role as modulator of the hypothalamic-pituitary-adrenal axis. The level of ... Read more...


Circadian changes in serum corticosterone levels affect hearing in mice exposed to noise.

15 Sep 2008 We assessed the relationship between changes in corticosterone concentrations and hearing in mice exposed to noise during the light (inactive) and dark (active) phases. Serum corticosterone concentrations and hearing levels were measured before, ... Read more...

 

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Technical information about 'Hypothalamo-Hypophyseal System'

Definition: A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

Descriptor UI: D007030

Alternative terms: Hypothalamo-Hypophyseal System; Hypothalamo Hypophyseal System; Hypothalamic-Pituitary Unit; Hypothalamic Pituitary Unit;

Related Mesh Headings: Pituitary Hormone-Releasing Hormones;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A06.688.357; A08.186.211.730.317.357.352.435; A08.713.357;

History Note: 65

Technical Notes: hypothalamo-pituitary-adrenal axis: coordinate HYPOTHALAMO-HYPOPHYSEAL SYSTEM + PITUITARY-ADRENAL SYSTEM; emphasis here is on interrelation between hypothalamus & pituitary: do not use as a substitute for HYPOTHALAMUS & PITUITARY GLAND as entities; diseases: coordinate IM with HYPOTHALAMIC DISEASES (IM)

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