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Your query 'hypoxia inducible factor' matched 204690 abstracts with 348587 hits. Returning the first 200 results.

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Articles 1 to 10 of 200:

Hypoxia-inducible factors, hypoxia, and tumor angiogenesis.

29 Apr 2006 PURPOSE OF REVIEW: The transcription factor hypoxia-inducible factor is activated by low oxygen to promote the expression of target genes that allow cellular, tissue, and organismal adaptation to low oxygen. Hypoxia-inducible factor is activated ...
rec_pub_16567961-hypoxia-inducible-factors-hypoxia-tumor-angiogenesis.htm

Inhibitory effect of hypoxia inducible factor-1 antisense oligonucleotide on growth of human hepatocellular carcinoma cells.

7 Aug 2007 OBJECT: To observe the inhibitory effect of Hypoxia inducible factor-1 antisense oligonuclecotide on growth of human hepatocellular carcinoma cells and gene expression of HIF-1, in order to seek a new gene therapy for hepatocellular carcinoma. ...
rec_pub_18188720-inhibitory-effect-hypoxia-inducible-factor-1-antisense.htm

Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.

9 Jul 2008 The aim of the study was to identify the impact on prognosis of hypoxia-inducible factor-1 genetic program in colorectal carcinomas and to develop an experimental procedure that would allow a reliable quantitative gene expression analysis in ...
rec_pub_18619649-up-regulation-hypoxia-inducible-factor-1-transcriptional-pathway.htm

ARC-111 inhibits hypoxia-mediated hypoxia-inducible factor-1alpha accumulation.

30 Mar 2007 ARC-111, a small-molecule topoisomerase I inhibitor, is a potent cytotoxic drug against multiple human cancer cell lines under normoxic conditions (Li et al., Cancer Res 2003; 63:8400-8407). In this study, we explore the potential of ARC-111 as a ...
rec_pub_17351396-arc-111-inhibits-hypoxia-mediated-hypoxia-inducible-factor-1alpha.htm

MSF-A interacts with hypoxia-inducible factor-1alpha and augments hypoxia-inducible factor transcriptional activation to affect tumorigenicity and angiogenesis.

13 Jan 2006 Hypoxia-inducible factor-1 (HIF-1) is a key transcription factor in the signaling pathway that controls the hypoxic responses of cancer cells. Activation of the HIF system has been observed in carcinogenesis and numerous cancers. We found an ...
rec_pub_16424018-msf-interacts-hypoxia-inducible-factor-1alpha-augments-hypoxia.htm

Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.

4 Jun 2007 The hypoxia-inducible factor (HIF) is a transcriptional factor with important roles in tumor biology. To clarify the possible involvement of the HIF-alpha subunit and von Hippel-Lindau (VHL) protein in the development and progression of ovarian ...
rec_pub_17555795-expression-hypoxia-inducible-factor-1alpha-hypoxia-inducible-factor.htm

Crinamine from Crinum asiaticum var. japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2.

29 Sep 2006 In a search for natural product inhibitors of hypoxia inducible factor-1 (HIF-1) function, crinamine (1), a crinane type alkaloid, showed potent dose dependent inhibition (IC50 = 2.7 microM) of HIF-1alpha in a cell-based reporter gene assay. ...
rec_pub_17015967-crinamine-crinum-asiaticum-var-japonicum-inhibits-hypoxia-inducible.htm

Expression of hypoxia-inducible factor-1 alpha and its prognostic significance in small-sized adenocarcinomas of the lung.

May 2006 OBJECTIVE: To analyze the prognostic value of hypoxia-inducible factor-1 (HIF-1) alpha expression and its correlation with clinicopathologic variables and the expression of vascular endothelial growth factor-A and -C in patients with lung ...
rec_pub_16675263-expression-hypoxia-inducible-factor-1-alpha-prognostic-significance.htm

Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.

9 Jun 2008 PURPOSE: We examined hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor-kappaB in acquired cystic disease of the kidney associated with renal cell carcinoma to elucidate the roles of these factors in cyst formation and ...
rec_pub_18550099-over-expression-hypoxia-inducible-protein-2-hypoxia-inducible-factor.htm

[Expression of hypoxia-inducible factor-1-alpha, hypoxia-inducible factor-2alpha and vascular endothelial growth factor in sporadic clear cell renal cell renal cell carcinoma and their significance in the pathogenesis thereof]

11 Jun 2006 OBJECTIVE: To investigate the expression of hypoxia-inducible factor (HIF)-1-alpha, HIF-2alpha, and vascular endothelial growth factor (VEGF) in sporadic clear cell renal cell carcinoma (CCRCC) and to analyze the relationship among them. METHODS: ...
rec_pub_16854277-expression-hypoxia-inducible-factor-1-alpha-hypoxia-inducible-factor.htm

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