Hypoxia-Ischemia, Brain - Therapy
Research News and Information

Sunday, November 22, 2009

Moderate hypothermia to treat perinatal asphyxial encephalopathy.

29 Sep 2009 BACKGROUND: Whether hypothermic therapy improves neurodevelopmental outcomes in newborn infants with asphyxial encephalopathy is uncertain. METHODS: We performed a randomized trial of infants who were less than 6 hours of age and had a gestational ... Read more...

Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischemic encephalopathy.

8 Sep 2009 PURPOSE: Therapeutic hypothermia reduces mortality and neurologic impairment in neonates with hypoxic-ischemic encephalopathy. Topiramate exerts a neuroprotective effect in asphyxiated neonatal animal models. However, no studies have investigated ... Read more...

Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2.

28 Jul 2009 BACKGROUND AND PURPOSE: The importance of bioactive lipid signaling under physiological and pathophysiological conditions is progressively becoming recognized. The disparate distribution of sphingosine kinase (SphK) isoform activity in normal and ... Read more...

Latest indexed articles for 'Hypoxia-Ischemia, Brain - Therapy'

These are the very latest articles for this heading:

• Moderate hypothermia to treat perinatal asphyxial encephalopathy. 29 Sep 2009
• Predictors of poor neurologic outcome after induced mild hypothermia following cardiac arrest. 20 Sep 2009
• Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischemic encephalopathy. 8 Sep 2009
• Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2. 28 Jul 2009
• Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse. 21 Jul 2009
• Pediatric neurointensive care: 2008 update for the Rogers' Textbook of Pediatric Intensive Care. 29 Jun 2009
• A hyperbaric oxygen therapy approach to heat stroke with multiple organ dysfunction. 28 Jun 2009
• Hypothermic inhibition of apoptotic pathways for combined neurotoxicity of iron and ascorbic acid in differentiated PC12 cells: reduction of oxidative stress and maintenance of the glutathione redox state. 10 Jun 2009
• Electroencephalographic monitoring during hypothermia after pediatric cardiac arrest. 31 May 2009
• [Protective effects of delayed multiple course hyperbaric oxygen treatment against hypoxic-ischemic brain damage in neonatal rats] 30 May 2009
• Hemispheric brain injury and behavioral deficits induced by severe neonatal hypoxia-ischemia in rats are not attenuated by intravenous administration of human umbilical cord blood cells. 30 May 2009
• Use of therapeutic hypothermia for term infants with hypoxic-ischemic encephalopathy. 30 May 2009
• Delivery room management of the newborn. 30 May 2009
• [Air or oxygen for neonatal resuscitation at birth?] 27 May 2009
• Induced hypothermia for infants with hypoxic- ischemic encephalopathy using a servo-controlled fan: an exploratory pilot study. 9 May 2009
• Post-ischemic hypothermia for 24h in P7 rats rescues hippocampal neuron: association with decreased astrocyte activation and inflammatory cytokine expression. May 2009
• [Effects of hyperbaric oxygen on intrauterine hypoxic-ischemic brain damage in neonatal rats] 29 Apr 2009
• Environmental experience modulates ischemia-induced amyloidogenesis and enhances functional recovery. 30 Mar 2009
• Effects of therapeutic hypothermia on multiorgan dysfunction in asphyxiated newborns: whole-body cooling versus selective head cooling. 24 Mar 2009
• Prognostic role of somatosensory and auditory evoked potentials in paediatric hypoxic-ischemic encephalopathy managed with hypothermia: an illustrative case. 15 Mar 2009

See a longer list of these articles.

Technical information about 'Hypoxia-Ischemia, Brain'

Definition: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.

Descriptor UI: D020925

Alternative terms: Hypoxia-Ischemia, Brain; Brain Hypoxia-Ischemias; Hypoxia Ischemia, Brain; Hypoxia-Ischemias, Brain; Brain Ischemia-Hypoxia; Brain Ischemia Hypoxia; Brain Ischemia-Hypoxias; Ischemia-Hypoxias, Brain; Ischemia-Hypoxia, Brain; Ischemia Hypoxia, Brain; Brain Hypoxia-Ischemia; Brain Hypoxia Ischemia; Hypoxic-Ischemic Encephalopathy; Encephalopathies, Hypoxic-Ischemic; Hypoxic Ischemic Encephalopathy; Hypoxic-Ischemic Encephalopathies; Ischemic-Hypoxic Encephalopathy; Encephalopathies, Ischemic-Hypoxic; Encephalopathy, Ischemic-Hypoxic; Ischemic Hypoxic Encephalopathy; Ischemic-Hypoxic Encephalopathies; Encephalopathy, Hypoxic-Ischemic; Encephalopathy, Hypoxic Ischemic; Anoxic-Ischemic Encephalopathy; Anoxic Ischemic Encephalopathy; Anoxic-Ischemic Encephalopathies; Encephalopathies, Anoxic-Ischemic; Encephalopathy, Anoxic-Ischemic; Encephalopathy, Anoxic Ischemic; Cerebral Hypoxia-Ischemia; Cerebral Hypoxia Ischemia; Cerebral Hypoxia-Ischemias; Hypoxia-Ischemias, Cerebral; Hypoxia-Ischemia, Cerebral; Hypoxia Ischemia, Cerebral; Ischemia-Hypoxia, Cerebral; Ischemia Hypoxia, Cerebral; Cerebral Ischemia-Hypoxia; Cerebral Ischemia Hypoxia; Cerebral Ischemia-Hypoxias; Ischemia-Hypoxias, Cerebral; Anoxia-Ischemia, Brain; Anoxia Ischemia, Brain; Anoxia-Ischemias, Brain; Brain Anoxia-Ischemias; Brain Ischemia-Anoxia; Brain Ischemia Anoxia; Brain Ischemia-Anoxias; Ischemia-Anoxias, Brain; Ischemia-Anoxia, Brain; Ischemia Anoxia, Brain; Brain Anoxia-Ischemia; Brain Anoxia Ischemia; Anoxia-Ischemia, Cerebral; Anoxia Ischemia, Cerebral; Anoxia-Ischemias, Cerebral; Cerebral Anoxia-Ischemias; Cerebral Ischemia-Anoxia; Cerebral Ischemia Anoxia; Cerebral Ischemia-Anoxias; Ischemia-Anoxias, Cerebral; Ischemia-Anoxia, Cerebral; Ischemia Anoxia, Cerebral; Cerebral Anoxia-Ischemia; Cerebral Anoxia Ischemia;

Related Mesh Headings: Anoxia;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.300.150.716; C10.228.140.624.500; C14.907.253.092.716;

History Note: 2000