 |
Immediate-Early Proteins
Research News and Information
Definition of 'Immediate-Early Proteins'Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals. Common names: Immediate-Early Proteins; Immediate Early Proteins; Proteins, Immediate-Early; Proteins, Immediate Early |
Sunday, November 22, 2009
30 Oct 2009 
Human papillomavirus (HPV)-induced carcinogenesis is critically dependent on the activities of the viral E6 and E7 oncogenes. Here, we demonstrate that expression of the putative tumor suppressor gene B-cell translocation gene-2 (BTG2) is reinduced ... Read more...
Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1.
23 Sep 2009 The role of SGK1 (serum- and glucocorticoid-induced protein kinase 1) in the glucocorticoid induction of alpha-ENaC (epithelial Na+ channel alpha subunit) gene transcription was explored by monitoring the transcriptional activity of a ... Read more...
11 Sep 2009 An important feature of the cerebral cortex is its layered organization, which is modulated in an area-specific manner. We found that the transcription factor AP2gamma regulates laminar fate in a region-specific manner. Deletion of AP2gamma (also ... Read more...
Latest indexed articles for 'Immediate-Early Proteins'
These are the very latest articles for this heading:
- Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 tumor suppressor gene. 30 Oct 2009
- Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1. 23 Sep 2009
- AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex. 11 Sep 2009
- Impaired mast cell activation in gene-targeted mice lacking the serum- and glucocorticoid-inducible kinase SGK1. 9 Sep 2009
- Myosin II is required for interkinetic nuclear migration of neural progenitors. 7 Sep 2009
- The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. 30 Aug 2009
- Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+ HCMV-specific cytotoxic T lymphocytes. 21 Aug 2009
- CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection. 17 Aug 2009
- Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels. 16 Aug 2009
- Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway. 15 Aug 2009
- ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells. 10 Aug 2009
- Complementation of a herpes simplex virus ICP0 null mutant by varicella-zoster virus ORF61p. 3 Aug 2009
- Stimulus duration and response time independently influence the kinetics of lytic cycle reactivation of Epstein-Barr virus. 3 Aug 2009
- Analysis of human cytomegalovirus-encoded microRNA activity during infection. 3 Aug 2009
- Pioglitazone induced gastric acid secretion. Aug 2009
- Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expression. 26 Jul 2009
- Temporal patterns of light-induced immediate-early gene expression in the suprachiasmatic nucleus. 24 Jul 2009
- Characterization of Singapore grouper iridovirus (SGIV) ORF086R, a putative homolog of ICP18 involved in cell growth control and virus replication. 22 Jul 2009
- Interaction of HCMV UL84 with C/EBPalpha transcription factor binding sites within oriLyt is essential for lytic DNA replication. 21 Jul 2009
- Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway. 15 Jul 2009
See a longer list of these articles.
Technical information about 'Immediate-Early Proteins'
Definition: Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
Registry Number: 0
Descriptor UI: D017874
Alternative terms: Immediate-Early Proteins; Immediate Early Proteins; Proteins, Immediate-Early; Proteins, Immediate Early;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.776.460; D12.776.964.925.968;
History Note: 94
Technical Notes: proteins coded by immed-early genes: read MeSH definition for history of "immediate-early"