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Immunity, Cellular - Research News and Information

Saturday, January 10, 2009

Definition of 'Immunity, Cellular'

Those manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place in the absence of circulating antibody or where antibody plays a subordinate role.

Common names: Immunity, Cellular; Cellular Immunities; Cellular Immunity; Immunities, Cellular; Cell-Mediated Immunity; Cell Mediated Immunity; Cell-Mediated Immunities; Immunities, Cell-Mediated; Immunity, Cell-Mediated

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Analysis of peripheral and local anti-tumor immune response in esophageal cancer patients after NY-ESO-1 protein vaccination.

13 Nov 2008 NY-ESO-1 antigen is a prototype of a class of cancer/testis antigens. We carried out a clinical trial using NY-ESO-1 whole protein as a cancer vaccine for 13 advanced cancer patients. We have recently reported that vaccine elicited humoral and ... Read more...


Impaired immunity to recall antigens and neoantigens in severely immunocompromised children and adolescents during the first year of effective highly active antiretroviral therapy.

13 Oct 2008 BACKGROUND: We studied whether severely immunocompromised, human immunodeficiency virus (HIV)-infected children who were beginning highly active antiretroviral therapy (HAART) or changing HAART regimens could spontaneously respond to a recall ... Read more...


Differential pathways govern CD4+ CD28- T cell proinflammatory and effector responses in patients with coronary artery disease.

13 Oct 2008 Patients with acute coronary syndromes experience circulatory and intraplaque expansion of an aggressive and unusual CD4(+) lymphocyte subpopulation lacking the CD28 receptor. These CD4(+)CD28(-) cells produce IFN-gamma and perforin, and are ... Read more...

 

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Technical information about 'Immunity, Cellular'

Definition: Those manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place in the absence of circulating antibody or where antibody plays a subordinate role.

Descriptor UI: D007111

Alternative terms: Immunity, Cellular; Cellular Immunities; Cellular Immunity; Immunities, Cellular; Cell-Mediated Immunity; Cell Mediated Immunity; Cell-Mediated Immunities; Immunities, Cell-Mediated; Immunity, Cell-Mediated;

Related Mesh Headings: Hypersensitivity, Delayed;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G12.450.555;

History Note: 72(70)

Technical Notes: IM general only, NIM with specific disease /immunol (IM): TN 242

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