Immunoglobulin E - Biosynthesis
Research News and Information

Monday, November 23, 2009

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells.

29 Sep 2009 Naturally arising regulatory T (Treg) cells express the transcription factor FoxP3, which critically controls the development and function of Treg cells. FoxP3 interacts with another transcription factor Runx1 (also known as AML1). Here, we showed ... Read more...

Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma.

19 Sep 2009 Polymorphisms in the interleukin-4 receptor alpha chain (IL-4R alpha) have been linked to asthma incidence and severity, but a causal relationship has remained uncertain. In particular, a glutamine to arginine substitution at position 576 (Q576R) of ... Read more...

Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization.

30 Aug 2009 BACKGROUND: Staphylococcus aureus (SA) in the nose can be a simple colonizer but also may create an intramucosal reservoir causing recurrent infections or can be a specific immune modulator through superantigenic mechanisms. Because the colonization ... Read more...

Latest indexed articles for 'Immunoglobulin E - Biosynthesis'

These are the very latest articles for this heading:

• Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells. 29 Sep 2009
• Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. 19 Sep 2009
• Associations between prenatal pesticide exposure and cough, wheeze, and IgE in early childhood. 17 Sep 2009
• Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization. 30 Aug 2009
• An IgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 promoter activity, and mRNA expression. 6 Aug 2009
• Immunotherapy in the treatment of food allergy. Does it have a future? 21 Jul 2009
• Effects of a DNA vaccine in an animal model of Alternaria alternata sensitivity. 28 Jun 2009
• Association between a common IL10 distal promoter haplotype and IgE production in individuals with atopic dermatitis. 20 Jun 2009
• The natural history and prognostic factors of egg allergy in Korean infants with atopic dermatitis. 30 May 2009
• Leuconostoc citreum HJ-P4 (KACC 91035) regulates immunoglobulin E in an ovalbumin-induced allergy model and induces interleukin-12 through nuclear factor-kappa B and p38/c-Jun N-terminal kinases signaling in macrophages. 30 May 2009
• Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production. 12 May 2009
• Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. 29 Apr 2009
• Liver X receptors control IgE expression in B cells. 29 Apr 2009
• The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen. 12 Apr 2009
• Allergen extract-induced interleukin-10 in human memory B cells inhibits immunoglobulin E production. 4 Apr 2009
• Suppressive effects of bifidobacterium breve strain M-16V on T-helper type 2 immune responses in a murine model. 30 Mar 2009
• TLR2/MyD88-dependent and -independent activation of mast cell IgE responses by the skin commensal yeast Malassezia sympodialis. 30 Mar 2009
• Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. 16 Mar 2009
• Inter-laboratory comparisons of assessment of the allergenic potential of proteins in mice. 27 Feb 2009
• Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice. 27 Feb 2009

See a longer list of these articles.

Technical information about 'Immunoglobulin E'

Definition: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Chemical name: Immunoglobulins, E

Registry Number: 37341-29-0

Descriptor UI: D007073

Alternative terms: Immunoglobulin E; E, Immunoglobulin; IgE;

Related Mesh Headings: Receptors, IgE;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; deficiency;

Pharmacological Action: Immunologic Factors;

Tree Number: D12.776.124.486.485.114.619.312; D12.776.124.790.651.114.619.312; D12.776.377.715.548.114.619.312;

History Note: 2002(1971)

Technical Notes: /defic = IMMUNOGLOBULIN E / defic + DYSGAMMAGLOBULINEMIA (IM); gammopathy: coordinate IMMUNOGLOBULIN E (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM), follow text;