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Immunoglobulin E - Blood
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Definition of 'Immunoglobulin E'

An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Common names: Immunoglobulin E; E, Immunoglobulin; IgE

More technical Information...

Saturday, November 21, 2009

Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge.

29 Sep 2009 BACKGROUND: Allergen-specific IgE antibodies are responsible for the pathogenesis of type I hypersensitivity. In patients with allergy, IgE titers can persist in the apparent absence of allergen for years. Seasonal allergen exposure triggers ... Read more...


Mechanisms of mast cell signaling in anaphylaxis.

29 Sep 2009 The recent development of a consensus definition and proposed diagnostic criteria for anaphylaxis offers promise for research efforts and a better understanding of the epidemiology and pathogenesis of this enigmatic and life-threatening disease. ... Read more...


Anaphylaxis: Recent advances in assessment and treatment.

29 Sep 2009 The incidence rate of anaphylaxis is increasing, particularly during the first 2 decades of life. Common triggers include foods, medications, and insect stings. Clinical diagnosis is based on a meticulous history of an exposure or event preceding ... Read more...

 

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Technical information about 'Immunoglobulin E'

Definition: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Chemical name: Immunoglobulins, E

Registry Number: 37341-29-0

Descriptor UI: D007073

Alternative terms: Immunoglobulin E; E, Immunoglobulin; IgE;

Related Mesh Headings: Receptors, IgE;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; deficiency;

Pharmacological Action: Immunologic Factors;

Tree Number: D12.776.124.486.485.114.619.312; D12.776.124.790.651.114.619.312; D12.776.377.715.548.114.619.312;

History Note: 2002(1971)

Technical Notes: /defic = IMMUNOGLOBULIN E / defic + DYSGAMMAGLOBULINEMIA (IM); gammopathy: coordinate IMMUNOGLOBULIN E (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM), follow text;

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