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Immunoglobulin E - Research News and Information

Saturday, January 10, 2009

Definition of 'Immunoglobulin E'

An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Common names: Immunoglobulin E; E, Immunoglobulin; IgE

More technical Information...

Fine ambient particles from various sites in europe exerted a greater IgE adjuvant effect than coarse ambient particles in a mouse model.

30 Dec 2008 In the European Union (EU)-funded project Respiratory Allergy and Inflammation due to Ambient Particles (RAIAP), coarse and fine ambient particulate matter (PM) was collected at traffic dominated locations in Oslo, Rome, Lodz, and Amsterdam, in the ... Read more...


High heritability but uncertain mode of inheritance for total serum IgE level and Schistosoma mansoni infection intensity in a schistosomiasis-endemic Brazilian population.

13 Oct 2008 BACKGROUND: Evidence of genetic control for total serum IgE (tIgE) level has been reported in multiple populations, although populations with substantial exposure to helminths have yielded lower estimates of heritability, despite evidence ... Read more...


Overproduction of IgE induces macrophage-derived chemokine (CCL22) secretion from basophils.

13 Oct 2008 Macrophage-derived chemokine (MDC) CCL22 is a potent chemoattractant for Th2 cells and has been implicated in Th2-predominant allergic inflammation. In the present study, we demonstrated that basophils produce MDC in response to monomeric IgE. In ... Read more...

 

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Technical information about 'Immunoglobulin E'

Definition: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Chemical name: Immunoglobulins, E

Registry Number: 37341-29-0

Descriptor UI: D007073

Alternative terms: Immunoglobulin E; E, Immunoglobulin; IgE;

Related Mesh Headings: Receptors, IgE;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; deficiency;

Pharmacological Action: Immunologic Factors;

Tree Number: D12.776.124.486.485.114.619.312; D12.776.124.790.651.114.619.312; D12.776.377.715.548.114.619.312;

History Note: 2002(1971)

Technical Notes: /defic = IMMUNOGLOBULIN E / defic + DYSGAMMAGLOBULINEMIA (IM); gammopathy: coordinate IMMUNOGLOBULIN E (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM), follow text;

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