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Immunoglobulin E
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Definition of 'Immunoglobulin E'

An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Common names: Immunoglobulin E; E, Immunoglobulin; IgE

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Saturday, November 21, 2009

Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge.

29 Sep 2009 BACKGROUND: Allergen-specific IgE antibodies are responsible for the pathogenesis of type I hypersensitivity. In patients with allergy, IgE titers can persist in the apparent absence of allergen for years. Seasonal allergen exposure triggers ... Read more...


Anaphylaxis syndromes related to a new mammalian cross-reactive carbohydrate determinant.

29 Sep 2009 Anaphylaxis is a severe allergic reaction that can rapidly progress and occasionally be fatal. In instances in which the triggering allergen is not obvious, establishing the cause of anaphylaxis is pivotal to long-term management. Assigning cause is ... Read more...


Mechanisms of mast cell signaling in anaphylaxis.

29 Sep 2009 The recent development of a consensus definition and proposed diagnostic criteria for anaphylaxis offers promise for research efforts and a better understanding of the epidemiology and pathogenesis of this enigmatic and life-threatening disease. ... Read more...

 

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Technical information about 'Immunoglobulin E'

Definition: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Chemical name: Immunoglobulins, E

Registry Number: 37341-29-0

Descriptor UI: D007073

Alternative terms: Immunoglobulin E; E, Immunoglobulin; IgE;

Related Mesh Headings: Receptors, IgE;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; deficiency;

Pharmacological Action: Immunologic Factors;

Tree Number: D12.776.124.486.485.114.619.312; D12.776.124.790.651.114.619.312; D12.776.377.715.548.114.619.312;

History Note: 2002(1971)

Technical Notes: /defic = IMMUNOGLOBULIN E / defic + DYSGAMMAGLOBULINEMIA (IM); gammopathy: coordinate IMMUNOGLOBULIN E (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM), follow text;

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