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Immunosuppression
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Definition of 'Immunosuppression'

Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.

Common names: Immunosuppression; Immunosuppressions; Therapy, Anti-Rejection; Anti-Rejection Therapy; Anti Rejection Therapy; Anti-Rejection Therapies; Therapy, Antirejection; Antirejection Therapies; Antirejection Therapy

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Sunday, November 22, 2009

Treatment of children with refractory anemia: the Japanese Childhood MDS Study Group trial (MDS99).

29 Nov 2009 BACKGROUND: Although hematopoietic stem cell transplantation (HSCT) is offered as a curative therapy for pediatric myelodysplastic syndrome (MDS), it may cause severe complications and mortality. Several reports have shown the efficacy of ... Read more...


Repopulation of vascularized bone allotransplants with recipient-derived cells: detection by laser capture microdissection and real-time PCR.

30 Oct 2009 Mechanisms underlying successful composite tissue transplantation must include an analysis of transplant chimerism, which is little studied, particularly in calcified tissue. We have developed a new method enabling determination of lineage of ... Read more...


Inflammatory bowel disease and lymphoproliferative disorders: the dust is starting to settle.

29 Sep 2009 The risk of lymphoproliferative disorders (LDs) has become a major concern for clinicians managing patients with inflammatory bowel disease (IBD). Yet it is difficult to distinguish the possible responsibility of immunosuppressive therapy from the ... Read more...

 

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Technical information about 'Immunosuppression'

Definition: Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.

Descriptor UI: D007165

Alternative terms: Immunosuppression; Immunosuppressions; Therapy, Anti-Rejection; Anti-Rejection Therapy; Anti Rejection Therapy; Anti-Rejection Therapies; Therapy, Antirejection; Antirejection Therapies; Antirejection Therapy;

Related Mesh Headings: Antilymphocyte Serum; Immune Tolerance; Immunocompromised Host;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E02.095.520.450; E05.478.610;

History Note: 72(71)

Technical Notes: note category: "deliberate prevention or diminution of the host's immune response": do not confuse with IMMUNOSUPPRESSION (PHYSIOLOGY) see IMMUNE TOLERANCE (G4); do not use /util except by MeSH definition; OPPORTUNISTIC INFECTIONS is available if particularly discussed: see note there

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