Indans
Research News and Information

Saturday, November 21, 2009

A double-blind, delayed-start trial of rasagiline in Parkinson's disease.

22 Sep 2009 BACKGROUND: A therapy that slows disease progression is the major unmet need in Parkinson's disease. METHODS: In this double-blind trial, we examined the possibility that rasagiline has disease-modifying effects in Parkinson's disease. A total of ... Read more...

Effect of a CYP2D6 polymorphism on the efficacy of donepezil in patients with Alzheimer disease.

6 Sep 2009 OBJECTIVE: To evaluate the influence of the single nucleotide polymorphism rs1080985 in the cytochrome P450 2D6 (CYP2D6) gene on the efficacy of donepezil in patients with mild to moderate Alzheimer disease (AD). METHODS: This was a multicenter, ... Read more...

Successful use of donepezil in treatment of cognitive impairment caused by maintenance electroconvulsive therapy: a case report.

30 Aug 2009 Cognitive deficits are commonly associated with maintenance electroconvulsive therapy (ECT). Treatment of these cognitive deficits is important but difficult. Cholinergic pathways are involved in these side effects, and donepezil, a cholinesterase ... Read more...

Latest indexed articles for 'Indans'

These are the very latest articles for this heading:

• Donepezil treatment of patients with MCI: a 48-week randomized, placebo- controlled trial. Nov 2009
• Turbocharging the brain. 29 Sep 2009
• Case report: combined use of donepezil and galantamine in mixed dementia. 29 Sep 2009
• Santhera licenses novel dyskinesia therapy to Biovail. 29 Sep 2009
• A double-blind, delayed-start trial of rasagiline in Parkinson's disease. 22 Sep 2009
• Effect of a CYP2D6 polymorphism on the efficacy of donepezil in patients with Alzheimer disease. 6 Sep 2009
• Successful use of donepezil in treatment of cognitive impairment caused by maintenance electroconvulsive therapy: a case report. 30 Aug 2009
• The effects of counseling spouse caregivers of people with Alzheimer disease taking donepezil and of country of residence on rates of admission to nursing homes and mortality. 30 Aug 2009
• Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial). 30 Aug 2009
• Strapped calix[4]pyrroles bearing a 1,3-indanedione at a beta-pyrrolic position: chemodosimeters for the cyanide anion. 18 Aug 2009
• Can cognitive enhancers reduce the risk of falls in older people with mild cognitive impairment? A protocol for a randomised controlled double blind trial. 10 Aug 2009
• Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium. 4 Aug 2009
• Acute cognitive effects of donepezil in young, healthy volunteers. 30 Jul 2009
• The inhibitory avoidance test optimized for discovery of cognitive enhancers. 30 Jul 2009
• The efficacy, safety, and tolerability of donepezil for the treatment of young adults with Down syndrome. 30 Jul 2009
• Donepezil improves episodic memory in young individuals vulnerable to the effects of sleep deprivation. 30 Jul 2009
• Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil. 30 Jul 2009
• How to manage overactive bladder in elderly individuals with dementia? A combined use of donepezil, a central acetylcholinesterase inhibitor, and propiverine, a peripheral muscarine receptor antagonist. 30 Jul 2009
• DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT. 22 Jul 2009
• Donepezil-induced adverse side effects of cardiac rhythm: 2 cases report of atrioventricular block and Torsade de Pointes. 13 Jul 2009

See a longer list of these articles.

Technical information about 'Indans'

Definition: Aryl CYCLOPENTANES that are a reduced (protonated) form of INDENES.

Registry Number: 0

Descriptor UI: D007189

Alternative terms: Indans; Indanones;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.455.426.559.847.486.487; D04.615.486.487;

Online Note: search INDENES 1966-74

History Note: 91(75)63-67; was see under INDENES 1975-90; was heading 1963-67