Indans - Research News and Information

Saturday, January 10, 2009

Donepezil: potential neuroprotective and disease-modifying effects.

29 Sep 2008 BACKGROUND: There is substantial evidence from preclinical studies that cholinesterase inhibitors affect basic processes that have been implicated in Alzheimer's disease (AD) pathogenesis, suggesting that these drugs should have both ... Read more...

Hydrophilic interaction chromatography-tandem mass spectrometry of donepezil in human plasma: application to a pharmacokinetic study of donepezil in volunteers.

18 Sep 2008 A selective, sensitive and rapid hydrophilic interaction liquid chromatography with electrospray ionization tandem mass spectrometry was developed for the determination of donepezil in human plasma. Donepezil was twice extracted from human plasma ... Read more...

Natural products as inspiration for the development of asymmetric catalysis.

16 Sep 2008 Biologically active natural products often contain particularly challenging structural features and functionalities in terms of synthesis. Perhaps the greatest difficulties are those caused by issues of stereochemistry. A useful strategy for ... Read more...

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Latest indexed articles for 'Indans'

These are the very latest articles for this heading:

• Donepezil: potential neuroprotective and disease-modifying effects. 29 Sep 2008
• Hydrophilic interaction chromatography-tandem mass spectrometry of donepezil in human plasma: application to a pharmacokinetic study of donepezil in volunteers. 18 Sep 2008
• Natural products as inspiration for the development of asymmetric catalysis. 16 Sep 2008
• Polyamine depletion with two different polyamine analogues causes DNA damage in human breast cancer cell lines. 30 Aug 2008
• Normal pressure hydrocephalus presenting as Othello syndrome: case presentation and review of the literature. 30 Aug 2008
• [Alzheimer type dementia] 30 Aug 2008
• Sensitive analysis of donepezil in plasma by capillary electrophoresis combining on-column field-amplified sample stacking and its application in Alzheimer's disease. 30 Aug 2008
• Acetylcholinesterase inhibitor in combination with cognitive training in older adults. 30 Aug 2008
• Drug utilization review of cholinesterase inhibitors in Quebec. 30 Aug 2008
• Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions. 13 Aug 2008
• Transtelephonic home blood pressure to assess the monoamine oxidase-B inhibitor rasagiline in Parkinson disease. 2 Aug 2008
• Randomized clinical trial results for donepezil in Alzheimer's disease: is the treatment glass half full or half empty? 30 Jul 2008
• Pestalachlorides A-C, antifungal metabolites from the plant endophytic fungus Pestalotiopsis adusta. 28 Jul 2008
• Results, rhetoric, and randomized trials: the case of donepezil. 22 Jul 2008
• The effect of donepezil on increased regional cerebral blood flow in the posterior cingulate cortex of a patient with Parkinson's disease dementia. 19 Jul 2008
• 2-Phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors: a study on the importance of modifications at the side chain on the activity. 8 Jul 2008
• Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes. 29 Jun 2008
• Prevalence of cholinesterase inhibitors in subjects with dementia in Europe. 29 Jun 2008
• Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase. 29 Jun 2008
• Anti-inflammatory activity of indanyltetrazole derivatives. 29 Jun 2008

See a longer list of these articles.

Technical information about 'Indans'

Definition: Aryl CYCLOPENTANES that are a reduced (protonated) form of INDENES.

Registry Number: 0

Descriptor UI: D007189

Alternative terms: Indans; Indanones;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.455.426.559.847.486.487; D04.615.486.487;

Online Note: search INDENES 1966-74

History Note: 91(75)63-67; was see under INDENES 1975-90; was heading 1963-67