Indoles - Research News and Information

Saturday, January 10, 2009

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial.

2 Nov 2008 BACKGROUND: Growth hormone secretion and muscle mass decline from midpuberty throughout life, culminating in sarcopenia, frailty, decreased function, and loss of independence. The decline of growth hormone in the development of sarcopenia is one of ... Read more...

Oxidative stress after uninephrectomy alters heart morphology in the apolipoprotein E -/- mouse.

30 Oct 2008 OBJECTIVE: Even minor reduction in glomerular filtration rate accelerates atherogenesis and increases cardiovascular risk. The current study on the apolipoprotein E -/- mouse was designed to investigate whether nephron reduction by uninephrectomy ... Read more...

The influence of statin medications on prostate-specific antigen levels.

26 Oct 2008 BACKGROUND: Recent data suggest that statin use may be associated with a reduced risk of advanced prostate cancer. However, the influence of statins on prostate-specific antigen (PSA) levels and what effect this could potentially have on prostate ... Read more...

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Latest indexed articles for 'Indoles'

These are the very latest articles for this heading:

• Summaries for patients. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults. 2 Nov 2008
• Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. 2 Nov 2008
• Use of growth hormone secretagogues to prevent or treat the effects of aging: not yet ready for prime time. 2 Nov 2008
• Oxidative stress after uninephrectomy alters heart morphology in the apolipoprotein E -/- mouse. 30 Oct 2008
• The influence of statin medications on prostate-specific antigen levels. 26 Oct 2008
• Statistical treatment of withdrawal in trials of anti-dementia drugs. 16 Oct 2008
• Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel. 13 Oct 2008
• Lynamicins A-E, chlorinated bisindole pyrrole antibiotics from a novel marine actinomycete. 7 Oct 2008
• Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma. 29 Sep 2008
• Phase II study of metronomic chemotherapy with thalidomide, carboplatin-vincristine-fluvastatin in the treatment of brain stem tumors in children. 29 Sep 2008
• Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity. 29 Sep 2008
• [Anti-angiogenic treatment in the management of metastatic renal cell carcinoma] 29 Sep 2008
• [Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma] 29 Sep 2008
• A genomic approach to identify molecular pathways associated with chemotherapy resistance. 29 Sep 2008
• Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes. 29 Sep 2008
• Calcium-activated potassium channels contribute to human coronary microvascular dysfunction after cardioplegic arrest. 28 Sep 2008
• Documentation of thyroid function in clinical studies with sunitinib: why does it matter? 27 Sep 2008
• 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation. 25 Sep 2008
• Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period. 23 Sep 2008
• Fabrication of ZnPc/protein nanohorns for double photodynamic and hyperthermic cancer phototherapy. 22 Sep 2008

See a longer list of these articles.

Technical information about 'Indoles'

Definition: Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.

Registry Number: 0

Descriptor UI: D007211

Alternative terms: Indoles;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.438.473;