Indoles
Research News and Information

Saturday, November 21, 2009

Localization of Rad50, a single-copy gene, on group 5 chromosomes of wheat, using a FISH protocol employing tyramide for signal amplification (Tyr-FISH).

25 Oct 2009 An indirect tyramide signal amplification FISH technique (Tyr-FISH) was adapted to detect single-copy genes in plants. In this study, Rad50 loci (responsible for a protein involved in the repair of breaks in double-stranded DNA) were localized on ... Read more...

Sex chromosome evolution in cotton stainers of the genus Dysdercus (Heteroptera: Pyrrhocoridae).

25 Oct 2009 The neo-X and neo-Y sex chromosomes of Dysdercus albofasciatus represent a unique model for the study of early stages of sex chromosome evolution since they retained the ability to pair and recombine, in contrast to sex chromosomes in most ... Read more...

Microdissection and chromosome painting of X and B chromosomes in the grasshopper Eyprepocnemis plorans.

25 Oct 2009 The relative location of 2 repetitive DNAs, i.e. ribosomal (rDNA) and a tandemly repeated satellite DNA (satDNA), with respect to the centromere, suggested that B chromosomes in the grasshopper Eyprepocnemis plorans derived intraspecifically from ... Read more...

Latest indexed articles for 'Indoles'

These are the very latest articles for this heading:

• Skin depigmentation induced by sunitinib treatment of renal cell carcinoma. 30 Oct 2009
• Localization of Rad50, a single-copy gene, on group 5 chromosomes of wheat, using a FISH protocol employing tyramide for signal amplification (Tyr-FISH). 25 Oct 2009
• Sex chromosome evolution in cotton stainers of the genus Dysdercus (Heteroptera: Pyrrhocoridae). 25 Oct 2009
• Microdissection and chromosome painting of X and B chromosomes in the grasshopper Eyprepocnemis plorans. 25 Oct 2009
• Kv7/KCNQ channels control action potential phasing of pyramidal neurons during hippocampal gamma oscillations in vitro. 19 Oct 2009
• A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication. 12 Oct 2009
• Phase II study of continuous daily sunitinib dosing in patients with previously treated advanced non-small cell lung cancer. 11 Oct 2009
• Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain. 6 Oct 2009
• Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies. 6 Oct 2009
• Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine-aplysinopsin hybrid molecule. 6 Oct 2009
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103). 6 Oct 2009
• Fundamental relationships between structure, reactivity, and biological activity for the duocarmycins and CC-1065. 6 Oct 2009
• Sorafenib reveals efficacy in sequential treatment of metastatic renal cell cancer. 29 Sep 2009
• Critical review of ropinirole and pramipexole - putative dopamine D(3)-receptor selective agonists - for the treatment of RLS. 29 Sep 2009
• Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist. 29 Sep 2009
• Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation. 29 Sep 2009
• Application of MOLMAP approach for QSAR modeling of various biological activities using substituent electronic descriptors. 29 Sep 2009
• INTS3 controls the hSSB1-mediated DNA damage response. 26 Sep 2009
• Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways. 26 Sep 2009
• Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss. 23 Sep 2009

See a longer list of these articles.

Technical information about 'Indoles'

Definition: Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.

Registry Number: 0

Descriptor UI: D007211

Alternative terms: Indoles;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.438.473;