Infertility, Male - Research News and Information

Saturday, January 10, 2009

A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis.

13 Nov 2008 LKB1 was discovered as a tumour suppressor mutated in Peutz-Jeghers syndrome, and is a gene involved in cell polarity as well as an upstream protein kinase for members of the AMP-activated protein kinase family. We report that mammals express two ... Read more...

LKB1: cancer, polarity, metabolism, and now fertility.

13 Nov 2008 The LKB1 serine/threonine kinase is a tumour suppressor responsible for the inherited familial cancer disorder Peutz-Jeghers syndrome and is inactivated in a large percentage of human lung cancers. LKB1 acts a master kinase, directly ... Read more...

Impact of male obesity on infertility: a critical review of the current literature.

29 Sep 2008 OBJECTIVE: To evaluate the current understanding of the effects and potential mechanisms of obesity on male fertility. DESIGN: Literature review of articles pertaining to obesity and male infertility. RESULT(S): Recent population-based studies ... Read more...

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Latest indexed articles for 'Infertility, Male'

These are the very latest articles for this heading:

• A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis. 13 Nov 2008
• LKB1: cancer, polarity, metabolism, and now fertility. 13 Nov 2008
• Use of hydroxyurea from childhood to adult age in sickle cell disease: semen analysis. 30 Oct 2008
• Impact of male obesity on infertility: a critical review of the current literature. 29 Sep 2008
• Inmate's infertility claim against prison officials dismissed. 29 Sep 2008
• Partial AZFc deletions and duplications: clinical correlates in the Italian population. 19 Sep 2008
• Microsurgical varicocelectomy for isolated asthenospermia. 16 Sep 2008
• How involved should the general urologist be in the evaluation and management of male infertility? 15 Sep 2008
• [Selenium deficiency and infertility. Andrologic aspects] 12 Sep 2008
• Reproductive tract complications associated with Chlamydia trachomatis infection in US Air Force males within 4 years of testing. 30 Aug 2008
• Transrectal ultrasonography in infertile patients with persistently elevated bacteriospermia. 30 Aug 2008
• Sperm DNA damage in men from infertile couples. 30 Aug 2008
• Why early surgery may not be enough: the search for new therapeutic strategies in cryptorchidism. 30 Aug 2008
• Increased sperm ubiquitination correlates with abnormal chromatin integrity. 30 Aug 2008
• Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice. 30 Aug 2008
• Idiopathic infertility in two captive male gerenuk (Litocranius walleri walleri). 30 Aug 2008
• [The role of Gilgamesh protein kinase in Drosophila melanogaster spermatogenesis] 30 Aug 2008
• Testicular histology in boys with Prader-Willi syndrome: fertile or infertile? 19 Aug 2008
• A complex genetic basis to X-linked hybrid male sterility between two species of house mice. 7 Aug 2008
• Parental translocations and need for preimplantation genetic diagnosis? Distorting effects of ascertainment bias and the need for information-rich families. Aug 2008

See a longer list of these articles.

Technical information about 'Infertility, Male'

Definition: The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Descriptor UI: D007248

Alternative terms: Infertility, Male; Male Infertility; Sterility, Male; Male Sterility;

Related Mesh Headings: Sperm Injections, Intracytoplasmic;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C12.294.365.700;

Online Note: use INFERTILITY, MALE to search STERILITY, MALE 1966-82

History Note: 83; was STERILITY, MALE 1963-82

Technical Notes: /chem ind permitted but not for testing of contraceptives