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Inflammation Mediators - Research News and Information

Saturday, January 10, 2009

Definition of 'Inflammation Mediators'

The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).

Common names: Inflammation Mediators; Mediators, Inflammation; Mediators of Inflammation

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New developments in mast cell biology.

30 Oct 2008 Mast cells can function as effector and immunoregulatory cells in immunoglobulin E-associated allergic disorders, as well as in certain innate and adaptive immune responses. This review focuses on exciting new developments in the field of mast cell ... Read more...


Inhibition of M current in sensory neurons by exogenous proteases: a signaling pathway mediating inflammatory nociception.

27 Oct 2008 Inflammatory pain is thought to be mediated in part through the action of inflammatory mediators on membrane receptors of peripheral nerve terminals, however, the downstream signaling events which lead to pain are poorly understood. In this study ... Read more...


Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.

13 Oct 2008 Efficient clearance of apoptotic cells (AC) by professional phagocytes is crucial for tissue homeostasis and resolution of inflammation. Macrophages respond to AC with an increase in antiinflammatory cytokine production but a diminished release of ... Read more...

 

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Technical information about 'Inflammation Mediators'

Definition: The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).

Registry Number: 0

Descriptor UI: D018836

Alternative terms: Inflammation Mediators; Mediators, Inflammation; Mediators of Inflammation;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; physiology;

Tree Number: D23.469;

History Note: 95

Technical Notes: do not confuse with ANTI-INFLAMMATORY AGENTS; DF: INFLAMM MEDIATORS

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