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Inflammation
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Definition of 'Inflammation'

A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Common names: Inflammation; Inflammations

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Sunday, November 22, 2009

Elevated serum macrophage migration inhibitory factor (MIF) concentrations in chronic kidney disease (CKD) are associated with markers of oxidative stress and endothelial activation.

6 Dec 2009 Chronic kidney disease (CKD) carries an increased risk of cardiovascular disease (CVD). Macrophage migration inhibiting factor (MIF) is a proinflammatory cytokine implicated in the pathogenesis of sepsis, autoimmune disease, atherogenesis, and ... Read more...


Identification and characterization of binding sites on S100A7, a participant in cancer and inflammation pathways.

8 Nov 2009 S100A7 (psoriasin) is a member of the S100 family of signaling proteins. It is implicated in and considered a therapeutic target for inflammation and cancer, yet no small molecule ligands for S100A7 have been identified. To begin the development of ... Read more...


Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases.

30 Oct 2009 The nuclear factor-kappaB (NF-kappaB) signalling pathway regulates immune responses and is implicated in the pathogenesis of many inflammatory diseases. Given the well established pro-inflammatory functions of NF-kappaB, inhibition of this pathway ... Read more...

 

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Technical information about 'Inflammation'

Definition: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Descriptor UI: D007249

Alternative terms: Inflammation; Inflammations;

Related Mesh Headings: Acute-Phase Reaction; Anti-Inflammatory Agents;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C23.550.470;

Technical Notes: IM general inflammatory process; look for specific inflamm dis in MeSH as -ITIS; NIM as coord for organ /dis not in MeSH as -ITIS; /drug ther: consider also ANTI-INFLAMMATORY AGENTS & its specifics; ACUTE PHASE REACTION (an early local inflammatory reaction to inj: see MeSH definition) is available; Manual 23.13+; DF: INFLAMM

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