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Inflammatory Bowel Diseases - Research News and Information

Saturday, January 10, 2009

Definition of 'Inflammatory Bowel Diseases'

Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

Common names: Inflammatory Bowel Diseases; Inflammatory Bowel Disease; Bowel Diseases, Inflammatory

More technical Information...

Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis.

15 Oct 2008 BACKGROUND: Trinitrobenzenesulphonic acid (TNBS) induced rat colitis is one of the most widely used models of inflammatory bowel disease (IBD), a condition whose aetiology and pathophysiology are incompletely understood. We have characterized this ... Read more...


Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation.

13 Oct 2008 The B7 costimulatory molecules govern many aspects of T cell immune responses by interacting with CD28 for costimulation, but also with CTLA-4 for immune suppression. Although blockade of CTLA-4 with Ab in humans undergoing cancer immune therapy ... Read more...


Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration.

13 Oct 2008 Neutrophil (PMN) infiltration and associated release of serine proteases contribute to epithelial injury during active phases of mucosal disorders such as inflammatory bowel disease. Previous studies have demonstrated that PMN contact with ... Read more...

 

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Technical information about 'Inflammatory Bowel Diseases'

Definition: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

Descriptor UI: D015212

Alternative terms: Inflammatory Bowel Diseases; Inflammatory Bowel Disease; Bowel Diseases, Inflammatory;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C06.405.205.731; C06.405.469.432;

History Note: 89

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