Injections, Intraperitoneal
Research News and Information

Sunday, November 22, 2009

Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.

13 Dec 2009 BACKGROUND: Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the ... Read more...

Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms.

5 Oct 2009 Anabolic androgenic steroids (AAS) can promote detrimental effects on social behaviors for which GABA type A (GABA(A)) receptor-mediated circuits in the forebrain play a critical role. While all AAS bind to androgen receptors (AR), they may also be ... Read more...

MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning.

29 Sep 2009 3,4-Methylenedioxymethamphetamine (MDMA) is a drug of abuse worldwide and a selective serotonin (5-HT) neurotoxin. An important factor in the risk of drug abuse and relapse is stress. Although multiple parallels exist between MDMA abuse and stress, ... Read more...

Latest indexed articles for 'Injections, Intraperitoneal'

These are the very latest articles for this heading:

• Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program. 13 Dec 2009
• Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. 5 Oct 2009
• MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning. 29 Sep 2009
• Assessing the role of the growth hormone secretagogue receptor in motivational learning and food intake. 29 Sep 2009
• Acute illness induces the release of aversive odor cues from adult, but not prepubertal, male rats and suppresses social investigation by conspecifics. 29 Sep 2009
• Critical role of TLR4 response in the activation of microglia induced by ethanol. 12 Sep 2009
• Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. 2 Sep 2009
• Toxic effect of methamphetamine on the retina of CD1 mice. 30 Aug 2009
• Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy. 30 Aug 2009
• Ovarian histology and follicular score in female rats treated with nandrolone decanoate and submitted to physical effort. 30 Aug 2009
• Phagocytosis of gadolinium chloride or zymosan induces simultaneous upregulation of hepcidin- and downregulation of hemojuvelin- and Fpn-1-gene expression in murine liver. 29 Aug 2009
• Neuroprotective effect of melatonin on experimental peripheral nerve injury: an electron microscopic and biochemical study. 19 Aug 2009
• ST1859 reduces prion infectivity and increase survival in experimental scrapie. 13 Aug 2009
• In utero transplantation of monocytic cells in cats with alpha-mannosidosis. 13 Aug 2009
• Attenuation of peripheral salt taste responses and local immune function contralateral to gustatory nerve injury: effects of aldosterone. 10 Aug 2009
• Indicators of oxidative stress and apoptosis in mouse whole lung and Clara cells following exposure to styrene and its metabolites. 6 Aug 2009
• Involvement of non-enzymatic antioxidant defenses in the protective effect of diphenyl diselenide on testicular damage induced by cadmium in mice. 3 Aug 2009
• Treatment of disseminated ovarian cancer using nonviral interleukin-12 gene therapy delivered intraperitoneally. 30 Jul 2009
• Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia. 30 Jul 2009
• Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Injections, Intraperitoneal'

Definition: Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.

Descriptor UI: D007274

Alternative terms: Injections, Intraperitoneal; Intraperitoneal Injections; Injection, Intraperitoneal; Intraperitoneal Injection;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E02.319.267.530.490;

History Note: 66(64)

Technical Notes: NIM; do not use /util except by MeSH definition; DF: INJECT INTRAPERITONEAL