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Insulin Resistance
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Definition of 'Insulin Resistance'

Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. It can be caused by the presence of INSULIN ANTIBODIES or the abnormalities in insulin receptors (RECEPTOR, INSULIN) on target cell surfaces. It is often associated with OBESITY; DIABETIC KETOACIDOSIS; INFECTION; and certain rare conditions. (from Stedman, 25th ed)

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Monday, November 23, 2009

High fat and highly thermolyzed fat diets promote insulin resistance and increase DNA damage in rats.

30 Oct 2009 Many studies have demonstrated that DNA damage may be associated with type 2 diabetes mellitus (T2DM) and its complications. The goal of this study was to evaluate the effects of the potential relationship between fat (thermolyzed) intake, glucose ... Read more...


Effect of 12-week tai chi chuan exercise on peripheral nerve modulation in patients with type 2 diabetes mellitus.

30 Oct 2009 OBJECTIVE: To examine the effect of tai chi chuan exercise on peripheral nerve modulation in patients with type 2 diabetes mellitus. DESIGN: Parallel group comparative study with a pre- and post- design. SUBJECTS: Twenty-eight participants with ... Read more...


Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity.

7 Oct 2009 Rats selectively bred for high endurance running capacity (HCR) have higher insulin sensitivity and improved metabolic health compared with those bred for low endurance capacity (LCR). We investigated several skeletal muscle characteristics, in ... Read more...

 

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Technical information about 'Insulin Resistance'

Definition: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. It can be caused by the presence of INSULIN ANTIBODIES or the abnormalities in insulin receptors (RECEPTOR, INSULIN) on target cell surfaces. It is often associated with OBESITY; DIABETIC KETOACIDOSIS; INFECTION; and certain rare conditions. (from Stedman, 25th ed)

Descriptor UI: D007333

Alternative terms: Insulin Resistance; Resistance, Insulin;

Allowable Qualifiers: ethnology; genetics; immunology; physiology; radiation effects;

Tree Number: C18.452.394.968.500; G07.690.320.617;

History Note: 67(64)

Technical Notes: for insulin resistance syndrome X use METABOLIC SYNDROME X

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