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Intercellular Signaling Peptides and Proteins - Genetics
Research News and Information
Definition of 'Intercellular Signaling Peptides and Proteins'Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal. Common names: Intercellular Signaling Peptides and Proteins; Paracrine Peptide Factors; Peptide Factors, Paracrine; Paracrine Protein Factors; Growth Factors |
Monday, November 23, 2009
The heritability and genetics of frontotemporal lobar degeneration.
Nov 2009 
BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a genetically and pathologically heterogeneous neurodegenerative disorder. METHODS: We collected blood samples from a cohort of 225 patients with a diagnosis within the FTLD spectrum and ... Read more...
30 Oct 2009 BACKGROUND: According to the cancer stem cell hypothesis, tumor growth is sustained by a subpopulation of cancer stem/progenitor-like cells. Self-renewal and high clonogenic potential are characteristics shared by normal stem and neoplastic ... Read more...
Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma.
30 Oct 2009 Stanniocalcin 2 (STC2) is a secreted glycoprotein of as yet unknown functions. We investigated STC2 in human neuroblastoma, the most common solid extra-cranial tumor of infancy. In primary tumor samples, we found that expression of STC2 is ... Read more...
Latest indexed articles for 'Intercellular Signaling Peptides and Proteins - Genetics'
These are the very latest articles for this heading:
- The heritability and genetics of frontotemporal lobar degeneration. Nov 2009
- In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue. 30 Oct 2009
- Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma. 30 Oct 2009
- Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes. 11 Oct 2009
- Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. 7 Oct 2009
- Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. 4 Oct 2009
- IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. 29 Sep 2009
- MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis. 29 Sep 2009
- Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis. 29 Sep 2009
- Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers. 29 Sep 2009
- The tetralogy of Fallot-associated G274D mutation impairs folding of the second epidermal growth factor repeat in Jagged-1. 21 Sep 2009
- Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation. 9 Sep 2009
- In vivo far-red luminescence imaging of a biomarker based on BRET from Cypridina bioluminescence to an organic dye. 6 Sep 2009
- CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity. 5 Sep 2009
- Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development. 30 Aug 2009
- An integrated view of the regulation of NKG2D ligands. 30 Aug 2009
- The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34(+) cord blood hematopoietic progenitor cells. 30 Aug 2009
- IL-18 activity in systemic lupus erythematosus. 30 Aug 2009
- Molecular pathology of early stage chemically induced hepatocarcinogenesis. 30 Aug 2009
- Growth and differentiation of the retina and the optic tectum in the medaka fish requires olSfrp5. 30 Aug 2009
See a longer list of these articles.
Technical information about 'Intercellular Signaling Peptides and Proteins'
Definition: Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
Registry Number: 0
Descriptor UI: D036341
Alternative terms: Intercellular Signaling Peptides and Proteins; Paracrine Peptide Factors; Peptide Factors, Paracrine; Paracrine Protein Factors; Growth Factors;
Related Mesh Headings: Receptors, Growth Factor; Paracrine Communication; Peptide Hormones;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D12.644.276; D12.776.467; D23.529;
History Note: 2003; for GROWTH FACTORS use GROWTH SUBSTANCES 1999-2006
Technical Notes: general or unspecified; prefer specifics; coordinate with PARACRINE COMMUNICATION if pertinent; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS is also available