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Intercellular Signaling Peptides and Proteins
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Definition of 'Intercellular Signaling Peptides and Proteins'

Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.

Common names: Intercellular Signaling Peptides and Proteins; Paracrine Peptide Factors; Peptide Factors, Paracrine; Paracrine Protein Factors; Growth Factors

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Monday, November 23, 2009

The heritability and genetics of frontotemporal lobar degeneration.

Nov 2009 BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a genetically and pathologically heterogeneous neurodegenerative disorder. METHODS: We collected blood samples from a cohort of 225 patients with a diagnosis within the FTLD spectrum and ... Read more...


Immediate implant placement into fresh extraction sites with chronic periapical pathologic features combined with plasma rich in growth factors: preliminary results of single-cohort study.

30 Oct 2009 PURPOSE: The purpose of this prospective study was to evaluate the clinical outcome of implants immediately placed into fresh extraction sockets of teeth affected by chronic periapical pathologic findings, using plasma rich in growth factors (PRGFs) ... Read more...


In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue.

30 Oct 2009 BACKGROUND: According to the cancer stem cell hypothesis, tumor growth is sustained by a subpopulation of cancer stem/progenitor-like cells. Self-renewal and high clonogenic potential are characteristics shared by normal stem and neoplastic ... Read more...

 

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Technical information about 'Intercellular Signaling Peptides and Proteins'

Definition: Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.

Registry Number: 0

Descriptor UI: D036341

Alternative terms: Intercellular Signaling Peptides and Proteins; Paracrine Peptide Factors; Peptide Factors, Paracrine; Paracrine Protein Factors; Growth Factors;

Related Mesh Headings: Receptors, Growth Factor; Paracrine Communication; Peptide Hormones;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.276; D12.776.467; D23.529;

History Note: 2003; for GROWTH FACTORS use GROWTH SUBSTANCES 1999-2006

Technical Notes: general or unspecified; prefer specifics; coordinate with PARACRINE COMMUNICATION if pertinent; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS is also available

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