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Interleukins - Research News and Information

Saturday, January 10, 2009

Definition of 'Interleukins'

Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types. They enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli.

Common names: Interleukins; Interleukin

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Effects of changing strategies of fracture fixation on immunologic changes and systemic complications after multiple trauma: damage control orthopedic surgery.

30 Oct 2008 In the treatment of polytrauma patients, multiple studies have shown how the timing and the type of the initial surgery of long bone fractures influence the incidence of systemic complications. Database analyses documented that unduly long surgical ... Read more...


Adjuvants LT-K63 and CpG enhance the activation of dendritic cells in neonatal mice.

30 Oct 2008 Dendritic cells (DC) play a major role in the priming of T cells and initiating specific immune responses. We assessed the effects of the adjuvants LT-K63 and CpG on neonatal DC in vivo and in vitro. Cytokine levels (IL-10, IL-12p70 and ... Read more...


Detecting the effects of selection at the population level in six bovine immune genes.

4 Oct 2008 BACKGROUND: The capacity of a species or population to respond to and survive novel infectious disease challenge is one of the most significant selective forces shaping genetic diversity and the period following animal domestication was likely one ... Read more...

 

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Technical information about 'Interleukins'

Definition: Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types. They enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli.

Registry Number: 0

Descriptor UI: D007378

Alternative terms: Interleukins; Interleukin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.276.374.465; D12.776.467.374.465; D23.529.374.465;

History Note: 1988; for MITOGENIC FACTORS, LYMPHOCYTE use INTERLEUKIN-2 1983-2001, LYMPHOKINES 1978-1982

Technical Notes: general or unspecified; prefer specifics

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