Interleukins - Research News and Information

Saturday, January 10, 2009

Effects of changing strategies of fracture fixation on immunologic changes and systemic complications after multiple trauma: damage control orthopedic surgery.

30 Oct 2008 In the treatment of polytrauma patients, multiple studies have shown how the timing and the type of the initial surgery of long bone fractures influence the incidence of systemic complications. Database analyses documented that unduly long surgical ... Read more...

Adjuvants LT-K63 and CpG enhance the activation of dendritic cells in neonatal mice.

30 Oct 2008 Dendritic cells (DC) play a major role in the priming of T cells and initiating specific immune responses. We assessed the effects of the adjuvants LT-K63 and CpG on neonatal DC in vivo and in vitro. Cytokine levels (IL-10, IL-12p70 and ... Read more...

Detecting the effects of selection at the population level in six bovine immune genes.

4 Oct 2008 BACKGROUND: The capacity of a species or population to respond to and survive novel infectious disease challenge is one of the most significant selective forces shaping genetic diversity and the period following animal domestication was likely one ... Read more...

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Latest indexed articles for 'Interleukins'

These are the very latest articles for this heading:

• Effects of changing strategies of fracture fixation on immunologic changes and systemic complications after multiple trauma: damage control orthopedic surgery. 30 Oct 2008
• Adjuvants LT-K63 and CpG enhance the activation of dendritic cells in neonatal mice. 30 Oct 2008
• Detecting the effects of selection at the population level in six bovine immune genes. 4 Oct 2008
• The IL-33/ST2 pathway: therapeutic target and novel biomarker. 29 Sep 2008
• A human dendritic cell subset receptive to the Venezuelan equine encephalitis virus-derived replicon particle constitutively expresses IL-32. 13 Sep 2008
• Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. 13 Sep 2008
• Effect of neonatal sublingual vaccination with native or denatured ovalbumin and adjuvant CpG or cholera toxin on systemic and mucosal immunity in mice. 10 Sep 2008
• Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation. 9 Sep 2008
• IL-21 signaling is critical for the development of type I diabetes in the NOD mouse. 6 Sep 2008
• Role of neutrophil recruitment in the amelioration of experimental colitis by genetic ablation of interleukin-21. 3 Sep 2008
• Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol. Sep 2008
• Interleukin-20 targets renal mesangial cells and is associated with lupus nephritis. Sep 2008
• Interleukin-21: biology and application to cancer therapy. 30 Aug 2008
• IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development. 30 Aug 2008
• Cytokine response in Balb/c mice infected with Francisella tularensis LVS and the Pohang isolate. 30 Aug 2008
• PET/CT examination in an anaplastic malignant lymphoma with extensive reactive involvement. 30 Aug 2008
• A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. 30 Aug 2008
• Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice. 30 Aug 2008
• IL-20 may contribute to the pathogenesis of human intervertebral disc herniation. 30 Aug 2008
• [Interleukin-20--a new target in psoriasis treatment] 30 Aug 2008

See a longer list of these articles.

Technical information about 'Interleukins'

Definition: Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types. They enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli.

Registry Number: 0

Descriptor UI: D007378

Alternative terms: Interleukins; Interleukin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.276.374.465; D12.776.467.374.465; D23.529.374.465;

History Note: 1988; for MITOGENIC FACTORS, LYMPHOCYTE use INTERLEUKIN-2 1983-2001, LYMPHOKINES 1978-1982

Technical Notes: general or unspecified; prefer specifics