Intracellular Space - Drug effects
Research News and Information

Sunday, November 22, 2009

Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells.

30 Oct 2009 Regulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells. We found that CCh (1 mM) significantly increased [Ca(2+)]i with 6-, ... Read more...

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes.

4 Oct 2009 Shiga-toxigenic Escherichia coli (STEC) use subtilase cytotoxin (SubAB) to interfere with adaptive immunity. Its inhibition of immunoglobulin secretion is both rapid and profound. SubAB favors cleavage of the newly synthesized immunoglobulin heavy ... Read more...

Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells.

29 Sep 2009 TRPA1 and TRPM8 are transient receptor potential (TRP) channels involved in sensory perception. TRPA1 is a non-selective calcium permeable channel activated by irritants and proalgesic agents. TRPM8 reacts to chemical cooling agents such as menthol. ... Read more...

Latest indexed articles for 'Intracellular Space - Drug effects'

These are the very latest articles for this heading:

• Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells. 30 Oct 2009
• Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes. 4 Oct 2009
• Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells. 29 Sep 2009
• Endogenous Jmjd6 gene product is expressed at the cell surface and regulates phagocytosis in immature monocyte-like activated THP-1 cells. 29 Sep 2009
• A new role of anandamide in human sperm: focus on metabolism. 29 Sep 2009
• Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers. 22 Sep 2009
• Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3. 22 Sep 2009
• Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells. 21 Sep 2009
• Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives. 8 Sep 2009
• Forward and reverse genetics to identify genes involved in the age-related resistance response in Arabidopsis thaliana. 30 Aug 2009
• Group B Streptococcus induces tyrosine phosphorylation of annexin V and glutathione S-transferase in human umbilical vein endothelial cells. 30 Aug 2009
• [Effect of estradiol on fluctuation of calcium in swine granulose cells stimulated by theophylline and prolactin] 30 Jul 2009
• Platelet-activating factor-stimulated production of reactive oxygen species in ovarian granulosa cells from periovulatory follicles. 30 Jul 2009
• Involvement of reactive oxygen species in apoptosis induced by pharmacological inhibition of protein kinase CK2. 30 Jul 2009
• Redox mechanisms involved in the selective activation of Nrf2-mediated resistance versus p53-dependent apoptosis in adenocarcinoma cells. 28 Jul 2009
• Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts. 27 Jul 2009
• Selective regulation of cellular and secreted multimeric adiponectin by antidiabetic therapies in humans. 19 Jul 2009
• Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists. 6 Jul 2009
• Large-scale production and study of a synthetic G protein-coupled receptor: human olfactory receptor 17-4. 4 Jul 2009
• Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Intracellular Space'

Definition: The area within CELLS.

Descriptor UI: D042541

Alternative terms: Intracellular Space; Intracellular Spaces; Space, Intracellular; Spaces, Intracellular; Subcellular Space; Space, Subcellular; Spaces, Subcellular; Subcellular Spaces;

Related Mesh Headings: Extracellular Space; Intracellular Fluid;

Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.284.430;

History Note: 2004