Introns
Research News and Information

Sunday, March 21, 2010

Fam83h is associated with intracellular vesicles and ADHCAI.

30 Oct 2009 Defects in FAM83H on human chromosome 8q24.3 cause autosomal-dominant hypocalcified amelogenesis imperfecta (ADHCAI). FAM83H does not encode a recognizable signal peptide, so we predicted that the Fam83h protein functions within the cell. We tested ... Read more...

Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3.

17 Oct 2009 BACKGROUND: Alternative splicing (AS) of maturing mRNA can generate structurally and functionally distinct transcripts from the same gene. Recent bioinformatic analyses of available genome databases inferred a positive correlation between intron ... Read more...

FGFR2 intronic polymorphisms interact with reproductive risk factors of breast cancer: results of a case control study in Japan.

13 Oct 2009 Recently, 2 genome-wide association studies demonstrated that single nucleotide polymorphisms (SNPs) of the fibroblast growth factor receptor 2 (FGFR2) gene at intron 2 are significantly associated with the risk of female breast cancer. As the next ... Read more...

Latest indexed articles for 'Introns'

These are the very latest articles for this heading:

• Tracking rates of transcription and splicing in vivo. 30 Oct 2009
• Regarding "Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association". 30 Oct 2009
• Fam83h is associated with intracellular vesicles and ADHCAI. 30 Oct 2009
• Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3. 17 Oct 2009
• FGFR2 intronic polymorphisms interact with reproductive risk factors of breast cancer: results of a case control study in Japan. 13 Oct 2009
• Rates of in situ transcription and splicing in large human genes. 9 Oct 2009
• Characterization of conserved tandem donor sites and intronic motifs required for alternative splicing in corticosteroid receptor genes. 7 Oct 2009
• The word landscape of the non-coding segments of the Arabidopsis thaliana genome. 6 Oct 2009
• CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. 6 Oct 2009
• Association of intronic variants of the BTBD9 gene with Tourette syndrome. 29 Sep 2009
• Comparative SNP diversity among four Eucalyptus species for genes from secondary metabolite biosynthetic pathways. 22 Sep 2009
• Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. 17 Sep 2009
• Single nucleotide polymorphism of rs430397 in the fifth intron of GRP78 gene and clinical relevance of primary hepatocellular carcinoma in Han Chinese: risk and prognosis. 13 Sep 2009
• Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. 6 Sep 2009
• Phylogenetic relationships and biogeography of the genus Algansea Girard (Cypriniformes: Cyprinidae) of central Mexico inferred from molecular data. 5 Sep 2009
• A potent enhancer element in the 5'-UTR intron is crucial for transcriptional regulation of the human ubiquitin C gene. Sep 2009
• A single-base substitution within an intronic repetitive element causes dominant retinitis pigmentosa with reduced penetrance. 30 Aug 2009
• [Intra-individual allele heterozygotes in phylogenetic analysis] 30 Aug 2009
• SOD1 haplotypes in familial keratoconus. 30 Aug 2009
• Comparative characterization of a temperature responsive gene (lactate dehydrogenase-B, ldh-b) in two congeneric tropical fish, Lates calcarifer and Lates niloticus. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Introns'

Definition: Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.

Descriptor UI: D007438

Alternative terms: Introns; Intron; Sequences, Intervening; Intervening Sequence; Sequence, Intervening; Intervening Sequences;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.360.340.024.220.400; G05.360.340.024.340.137.515;

Online Note: use BASE SEQUENCE to search INTRONS & INTERVENING SEQUENCES 1981-86

History Note: 87; INTERVENING SEQUENCES & INTRONS were see BASE SEQUENCE 1981-86