Iodide Peroxidase - Research News and Information

Saturday, January 10, 2009

Clinical inquiries: How useful are autoantibodies in diagnosing thyroid disorders?

30 Aug 2008 They're useful in diagnosing Graves' disease and, to a lesser extent, autoimmune thyroid disease; they can also help predict hypothyroidism. Thyrotropin receptor antibodies (TRAb) may be mildly elevated in a variety of thyroid disorders, but a TRAb ... Read more...

Prediction of progression to overt hypothyroidism or hyperthyroidism in female relatives of patients with autoimmune thyroid disease using the Thyroid Events Amsterdam (THEA) score.

9 Aug 2008 BACKGROUND: Genetic and environmental factors are involved in the pathogenesis of autoimmune thyroid disease (AITD). Family members of patients with AITD are at increased risk for AITD, but not all will develop overt hypothyroidism or ... Read more...

Ancestral TSH mechanism signals summer in a photoperiodic mammal.

3 Aug 2008 In mammals, day-length-sensitive (photoperiodic) seasonal breeding cycles depend on the pineal hormone melatonin, which modulates secretion of reproductive hormones by the anterior pituitary gland [1]. It is thought that melatonin acts in the ... Read more...

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Latest indexed articles for 'Iodide Peroxidase'

These are the very latest articles for this heading:

• Clinical inquiries: How useful are autoantibodies in diagnosing thyroid disorders? 30 Aug 2008
• Prediction of progression to overt hypothyroidism or hyperthyroidism in female relatives of patients with autoimmune thyroid disease using the Thyroid Events Amsterdam (THEA) score. 9 Aug 2008
• Ancestral TSH mechanism signals summer in a photoperiodic mammal. 3 Aug 2008
• Regulation of mammary gland sensitivity to thyroid hormones during the transition from pregnancy to lactation. 16 Jul 2008
• Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth. 5 Jul 2008
• Thyroid autoimmunity in schoolchildren in an area with long-standing iodine sufficiency: correlation with gender, pubertal stage, and maternal thyroid autoimmunity. 29 Jun 2008
• Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothyroxine. 29 Jun 2008
• Factors influencing the study of peroxidase-generated iodine species and implications for thyroglobulin synthesis. 29 Jun 2008
• [The effect of selenium therapy on autoimmune thyroiditis] 27 Jun 2008
• Is euthyroid sick syndrome a defensive mechanism against oxidative stress? Jun 2008
• The evolution of the DLK1-DIO3 imprinted domain in mammals. Jun 2008
• Genomic imprinting at the mammalian Dlk1-Dio3 domain. 30 May 2008
• Screening pregnant women for autoimmune thyroid disease: a cost-effectiveness analysis. 30 May 2008
• BRAFV600E mutation, but not RET/PTC rearrangements, is correlated with a lower expression of both thyroperoxidase and sodium iodide symporter genes in papillary thyroid cancer. 30 May 2008
• Effects of selenium supplementation on TPOAb and cytokines in acute autoimmune thyroiditis. 30 May 2008
• There is immunological benefit of selenium treatment in autoimmune thyroiditis. 30 May 2008
• Neurodevelopmental and neurophysiological actions of thyroid hormone. 30 May 2008
• Photoperiodic signalling through the melatonin receptor turns full circle. 30 May 2008
• Short-term effect of soy consumption on thyroid hormone levels and correlation with phytoestrogen level in healthy subjects. 30 May 2008
• Functional significance of a truncated thyroid receptor subtype lacking a hormone-binding domain in goldfish. 27 May 2008

See a longer list of these articles.

Technical information about 'Iodide Peroxidase'

Definition: A hemeprotein that catalyzes the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly proteins. EC 1.11.1.8.

Chemical name: Iodide:hydrogen-peroxide oxidoreductase

Registry Number: EC 1.11.1.8

Descriptor UI: D007453

Alternative terms: Iodide Peroxidase; Peroxidase, Iodide; Deiodinase; Thyroid Peroxidase; Peroxidase, Thyroid; Iodotyrosine Deiodase; Deiodase, Iodotyrosine; Iodotyrosine Deiodinase; Deiodinase, Iodotyrosine; Monodeiodinase; 5'-Deiodinase; 5' Deiodinase; Iodinase; Iodothyronine Deiodinase; Deiodinase, Iodothyronine; Reverse Triiodothyronine 5'-Deiodinase; 5'-Deiodinase, Reverse Triiodothyronine; Reverse Triiodothyronine 5' Deiodinase; Triiodothyronine 5'-Deiodinase, Reverse; Triiodothyronine Deiodinase; Deiodinase, Triiodothyronine; Tetraiodothyronine 5'-Deiodinase; 5'-Deiodinase, Tetraiodothyronine; Tetraiodothyronine 5' Deiodinase; T4-5'-Deiodinase; T4 5' Deiodinase; Thyroxine 5'-Deiodinase; 5'-Deiodinase, Thyroxine; Thyroxine 5' Deiodinase; Thyroxine 5'-Monodeiodinase; 5'-Monodeiodinase, Thyroxine; Thyroxine 5' Monodeiodinase; Thyroxine Converting Enzyme; Enzyme, Thyroxine Converting; Iodothyronine 5'-Deiodinase; 5'-Deiodinase, Iodothyronine; Iodothyronine 5' Deiodinase; T4-Monodeiodinase; T4 Monodeiodinase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.682.732.525;

History Note: 86(76); was see under PEROXIDASES 1976-85

Technical Notes: /defic: consider also MONOIODOTYROSINE /metab (IM) + AMINO ACID METABOLISM, INBORN ERRORS (IM) + CONGENITAL HYPOTHYROIDISM