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Isoenzymes - Analysis
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Definition of 'Isoenzymes'

Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.

Common names: Isoenzymes; Isozymes; Alloenzymes; Allozymes

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Sunday, November 22, 2009

Diclofenac sodium inhibits NFkappaB transcription in osteoclasts.

30 Oct 2009 A non-steroidal anti-inflammatory drug, diclofenac, acts efficiently against inflammation; however, down-regulation of diclofenac on bone remodeling has raised concerns. The inhibitory mechanisms of diclofenac are poorly understood. We hypothesized ... Read more...


CCR5 down-regulates osteoclast function in orthodontic tooth movement.

30 Oct 2009 During orthodontic tooth movement, there is local production of chemokines and an influx of leukocytes into the periodontium. CCL5 plays an important role in osteoclast recruitment and activation. This study aimed to investigate whether the ... Read more...


The influence of thyroid hormones on periodontitis-related bone loss and tooth-supporting alveolar bone: a histological study in rats.

20 Oct 2009 BACKGROUND AND OBJECTIVE: Recent studies have pointed to potentially periodontal risk indicators, however no information is available on the impact of changes in thyroid hormone levels on the progression of periodontitis and on the quality of ... Read more...

 

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Technical information about 'Isoenzymes'

Definition: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.

Registry Number: 0

Descriptor UI: D007527

Alternative terms: Isoenzymes; Isozymes; Alloenzymes; Allozymes;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.348; D12.776.800.300;

History Note: 67(65)

Technical Notes: IM general only; coordinate NIM with specific enzyme (IM)

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