Isoenzymes - Metabolism
Research News and Information

Sunday, November 22, 2009

Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling.

29 Nov 2009 The role of OxLDL in the generation and progression of atherosclerosis is well admitted. In addition, it is well known that atherosclerosis is often accompanied by perturbations in bone remodeling, resulting in osteoporosis. In the current studies, ... Read more...

Kinetics of transport and phosphorylation of glucose in cancer cells.

29 Nov 2009 Metabolic control analysis of tumor glycolysis has indicated that hexokinase (HK) and glucose transporter (GLUT) exert the main flux control (71%). To understand why they are the main controlling steps, the GLUT and HK kinetics and the contents of ... Read more...

Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity.

29 Nov 2009 Receptor activator NF-kappaB ligand (RANKL)-activated signaling is essential for osteoclast differentiation, activation and survival. Caffeic acid phenethyl ester (CAPE), a natural NF-kappaB inhibitor from honeybee propolis has been shown to have ... Read more...

Latest indexed articles for 'Isoenzymes - Metabolism'

These are the very latest articles for this heading:

• Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. 29 Nov 2009
• Kinetics of transport and phosphorylation of glucose in cancer cells. 29 Nov 2009
• Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity. 29 Nov 2009
• Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts. 29 Nov 2009
• Cyclin-dependent kinases: a family portrait. 30 Oct 2009
• Cytokines and signaling pathways regulating matrix metalloproteinase-9 (MMP-9) expression in corneal epithelial cells. 30 Oct 2009
• Cocultures of osteoblasts and osteoclasts are influenced by local application of zoledronic acid incorporated in a poly(D,L-lactide) implant coating. 29 Sep 2009
• Titanium IV ions induced human osteoclast differentiation and enhanced bone resorption in vitro. 29 Sep 2009
• A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function: enhanced transfection efficiency before and after differentiation. 29 Sep 2009
• Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cells. 29 Sep 2009
• Local delivery of EGF-liposome mediated bone modeling in orthodontic tooth movement by increasing RANKL expression. 27 Sep 2009
• Investigation of electrogenic partial reactions in detergent-solubilized Na,K-ATPase. 27 Sep 2009
• Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. 25 Sep 2009
• The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity. 23 Sep 2009
• Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti. 20 Sep 2009
• Physiology and posttranscriptional regulation of methanol:coenzyme M methyltransferase isozymes in Methanosarcina acetivorans C2A. 16 Sep 2009
• Arabidopsis thaliana mitochondrial glyoxalase 2-1 exhibits beta-lactamase activity. 13 Sep 2009
• Interactions between large and small subunits of different acetohydroxyacid synthase isozymes of Escherichia coli. 13 Sep 2009
• Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2. 13 Sep 2009
• Why do phosphatidylinositol kinases have so many isoforms? 12 Sep 2009

See a longer list of these articles.

Technical information about 'Isoenzymes'

Definition: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.

Registry Number: 0

Descriptor UI: D007527

Alternative terms: Isoenzymes; Isozymes; Alloenzymes; Allozymes;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.348; D12.776.800.300;

History Note: 67(65)

Technical Notes: IM general only; coordinate NIM with specific enzyme (IM)