Isosorbide Dinitrate - Therapeutic use
Research News and Information

Sunday, November 22, 2009

Heart failure in women: a need for prospective data.

2 Aug 2009 Heart failure affects 5 million Americans, and nearly 50% of these are women. Sex differences have been noted regarding the underlying etiology, pathophysiology, and prognosis. Women are less likely to have coronary artery disease and more likely ... Read more...

Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure.

18 Jul 2009 Hypertension-induced diastolic heart failure accounts for a large proportion of all heart failure presentations. Hypertension also induces left ventricular (LV) hypertrophy. Fixed-dose isosorbide dinitrate/hydralazine (HISDN) decreased mortality in ... Read more...

Efficacy of beta-adrenergic blocker plus 5-isosorbide mononitrate and endoscopic band ligation for prophylaxis of esophageal variceal rebleeding: a meta-analysis.

5 May 2009 AIM: To systematically assess the efficacy and safety of beta-adrenergic blocker plus 5-isosorbide mononitrate (BB + ISMN) and endoscopic band ligation (EBL) on prophylaxis of esophageal variceal rebleeding. METHODS: Randomized controlled trials ... Read more...

Latest indexed articles for 'Isosorbide Dinitrate - Therapeutic use'

These are the very latest articles for this heading:

• [Importance of drug treatment to lower portal pressure in the therapy of variceal bleeding] 31 Aug 2009
• Heart failure in women: a need for prospective data. 2 Aug 2009
• Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure. 18 Jul 2009
• Efficacy of beta-adrenergic blocker plus 5-isosorbide mononitrate and endoscopic band ligation for prophylaxis of esophageal variceal rebleeding: a meta-analysis. 5 May 2009
• Propranolol, isosorbide mononitrate and endoscopic band ligation - alone or in varying combinations for the prevention of esophageal variceal rebleeding. 29 Apr 2009
• Effectiveness of hydralazine/isosorbide dinitrate in racial/ethnic subgroups with heart failure. 27 Feb 2009
• Have we witnessed the rise and fall of race-specific drugs? 27 Feb 2009
• LA-419, a nitric-oxide donor for the treatment of cardiovascular disorders. 27 Feb 2009
• Nadolol plus isosorbide mononitrate alone or associated with band ligation in the prevention of recurrent bleeding: a multicentre randomised controlled trial. 10 Feb 2009
• Topical anal fissure treatment: placebo-controlled study of mononitrate and trinitrate therapies. 8 Jan 2009
• Non-hemodynamic effects of organic nitrates and the distinctive characteristics of pentaerithrityl tetranitrate. 30 Dec 2008
• Race-based medicine and justice as recognition: exploring the phenomenon of BiDil. 30 Dec 2008
• From the editors. 30 Dec 2008
• Cervical priming in the first trimester: morphological and biochemical effects of misoprostol and isosorbide mononitrate. 30 Dec 2008
• Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial. 21 Dec 2008
• Nitric oxide-releasing agent, LA419, reduces atherogenesis in apolipoprotein E-deficient mice. Dec 2008
• Isosorbide dinitrate/hydralazine: its role in the treatment of heart failure. 29 Nov 2008
• [Recent findings on nitrates: their action, bioactivation and development of tolerance] 20 Oct 2008
• Isosorbide mononitrate versus alendronate for postmenopausal osteoporosis. 19 Sep 2008
• Use of terahertz electromagnetic radiation for correction of blood rheology parameters in patients with unstable angina under conditions of treatment with isoket, an NO donor. 30 Aug 2008

See a longer list of these articles.

Technical information about 'Isosorbide Dinitrate'

Definition: A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.

Chemical name: D-Glucitol, 1,4:3,6-dianhydro-, dinitrate

Registry Number: 87-33-2

Descriptor UI: D007548

Alternative terms: Isosorbide Dinitrate; Dinitrate, Isosorbide; Dilatrate; Iso-Bid; Iso Bid; IsoBid; Isodinit; Isoket; Sorbonit; Isomak R; Isordil; Isotrate; Nitrosorbide; Sorbitrate; Cardonit 40; Isoket Retard-120; Isoket Retard 120; Isoket Retard120;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Vasodilator Agents; Nitric Oxide Donors;

Tree Number: D02.033.800.813.480.500; D09.853.813.480.500;

History Note: 74(66)