Isosorbide Dinitrate
Research News and Information

Sunday, November 22, 2009

Impact of multiaccess infusion devices on in vitro drug delivery during multi-infusion therapy.

29 Sep 2009 BACKGROUND: Multiaccess infusion sets allow multiple simultaneous infusions but may induce interference in drug delivery resulting from large variations in the delivery rate of potent drugs. In this study, we sought to understand the influence of ... Read more...

Heart failure in women: a need for prospective data.

2 Aug 2009 Heart failure affects 5 million Americans, and nearly 50% of these are women. Sex differences have been noted regarding the underlying etiology, pathophysiology, and prognosis. Women are less likely to have coronary artery disease and more likely ... Read more...

Randomised placebo-controlled trial of outpatient (at home) cervical ripening with isosorbide mononitrate (IMN) prior to induction of labour--clinical trial with analyses of efficacy and acceptability. The IMOP study.

30 Jul 2009 OBJECTIVE: To determine whether isosorbide mononitrate (IMN), self-administered vaginally by women at home, improves the process of induction of labour. DESIGN: Randomised double blind placebo-controlled trial. SETTING: Large UK maternity hospital. ... Read more...

Latest indexed articles for 'Isosorbide Dinitrate'

These are the very latest articles for this heading:

• Impact of multiaccess infusion devices on in vitro drug delivery during multi-infusion therapy. 29 Sep 2009
• [Importance of drug treatment to lower portal pressure in the therapy of variceal bleeding] 31 Aug 2009
• Heart failure in women: a need for prospective data. 2 Aug 2009
• Randomised placebo-controlled trial of outpatient (at home) cervical ripening with isosorbide mononitrate (IMN) prior to induction of labour--clinical trial with analyses of efficacy and acceptability. The IMOP study. 30 Jul 2009
• Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure. 18 Jul 2009
• The cost-effectiveness of outpatient (at home) cervical ripening with isosorbide mononitrate prior to induction of labour. 26 May 2009
• Addition of propranolol and isosorbide mononitrate to endoscopic variceal ligation does not reduce variceal rebleeding incidence. 25 May 2009
• Efficacy of beta-adrenergic blocker plus 5-isosorbide mononitrate and endoscopic band ligation for prophylaxis of esophageal variceal rebleeding: a meta-analysis. 5 May 2009
• Propranolol, isosorbide mononitrate and endoscopic band ligation - alone or in varying combinations for the prevention of esophageal variceal rebleeding. 29 Apr 2009
• Comparison of exercise-rest-reinjection Tl-201 imaging and rest sublingual isosorbide dinitrate Tc-99m MIBI imaging for the assessment of myocardial viability. 20 Apr 2009
• Comparison of intracoronary adenosine and isosorbide dinitrate on no-reflow/slow flow during rotational atherectomy. 30 Mar 2009
• Development of monolithic osmotic pump tablet system for isosorbide-5-mononitrate delivery and evaluation of it in vitro and in vivo. 30 Mar 2009
• Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root extract. 24 Mar 2009
• Effectiveness of hydralazine/isosorbide dinitrate in racial/ethnic subgroups with heart failure. 27 Feb 2009
• Have we witnessed the rise and fall of race-specific drugs? 27 Feb 2009
• LA-419, a nitric-oxide donor for the treatment of cardiovascular disorders. 27 Feb 2009
• Usefulness of Isosorbide Dinitrate and Hydralazine as add-on therapy in patients discharged for advanced decompensated heart failure. 19 Feb 2009
• Nadolol plus isosorbide mononitrate alone or associated with band ligation in the prevention of recurrent bleeding: a multicentre randomised controlled trial. 10 Feb 2009
• Effect of several electrolyzed waters on the skin permeation of lidocaine, benzoic Acid, and isosorbide mononitrate. 30 Jan 2009
• Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production. 28 Jan 2009

See a longer list of these articles.

Technical information about 'Isosorbide Dinitrate'

Definition: A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.

Chemical name: D-Glucitol, 1,4:3,6-dianhydro-, dinitrate

Registry Number: 87-33-2

Descriptor UI: D007548

Alternative terms: Isosorbide Dinitrate; Dinitrate, Isosorbide; Dilatrate; Iso-Bid; Iso Bid; IsoBid; Isodinit; Isoket; Sorbonit; Isomak R; Isordil; Isotrate; Nitrosorbide; Sorbitrate; Cardonit 40; Isoket Retard-120; Isoket Retard 120; Isoket Retard120;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Vasodilator Agents; Nitric Oxide Donors;

Tree Number: D02.033.800.813.480.500; D09.853.813.480.500;

History Note: 74(66)