Ketone Bodies
Research News and Information

Sunday, November 22, 2009

Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver.

6 Aug 2009 We investigated the interrelations between C(4) ketogenesis (production of beta-hydroxybutyrate + acetoacetate), C(5) ketogenesis (production of beta-hydroxypentanoate + beta-ketopentanoate), and anaplerosis in isolated rat livers perfused with ... Read more...

Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia.

30 Jul 2009 Ketogenesis, inferred by the production of acetoacetate plus ss-hydroxybutyrate, in isolated perfused livers from 24-h fasted diabetic rats submitted to short-term insulin-induced hypoglycemia (IIH) was investigated. For this purpose, ... Read more...

Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

7 Jul 2009 Fibroblast growth factors (Fgfs) are polypeptide growth factors with diverse functions. Fgf21, a unique member of the Fgf family, is expected to function as a metabolic regulator in an endocrine manner. Hepatic Fgf21 expression was increased by ... Read more...

Latest indexed articles for 'Ketone Bodies'

These are the very latest articles for this heading:

• Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver. 6 Aug 2009
• Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia. 30 Jul 2009
• Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver. 7 Jul 2009
• Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis. Jul 2009
• GABA action in immature neocortical neurons directly depends on the availability of ketone bodies. 20 Jun 2009
• Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation. 20 Jun 2009
• [Case report of dentatorubral pallidoluysian atrophy in a patient on a ketogenic diet] 30 May 2009
• Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons. 16 May 2009
• [Transient bilateral complete blindness and severe abdominal pain in a patient with alcoholic ketoacidosis] 29 Apr 2009
• Prevention of diabetic ketoacidosis and self-monitoring of ketone bodies: an overview. 29 Apr 2009
• The ketogenic diet has no effect on the expression of spike-and-wave discharges and nutrient transporters in genetic absence epilepsy rats from Strasbourg. 29 Apr 2009
• Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease. 29 Apr 2009
• Metabolic response to a ketogenic breakfast in the healthy elderly. 30 Mar 2009
• Tolerance to fast: rational and practical evaluation in children with hypoketonaemia. 2 Mar 2009
• No change of body mass, fat mass, and skeletal muscle mass in ultraendurance swimmers after 12 hours of swimming. 27 Feb 2009
• Management of pitfalls for the successful clinical use of hypothermia treatment. 27 Feb 2009
• Effects of insulin on ketogenesis following fasting in lean and obese men. 17 Feb 2009
• Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice. 31 Jan 2009
• Impact of hyperketonemia in early lactation dairy cows on health and production. 30 Jan 2009
• Effects of very-low-carbohydrate (horsemeat- or beef-based) diets and restricted feeding on weight gain, feed and energy efficiency, as well as serum levels of cholesterol, triacylglycerol, glucose, insulin and ketone bodies in adult rats. 7 Jan 2009

See a longer list of these articles.

Technical information about 'Ketone Bodies'

Definition: The substances beta-hydroxybutyric acid, acetoacetic acid, and acetone, which are produced by fatty acid and carbohydrate metabolism in the liver in approximately a 78:20:2 ratio. Acetoacetate is produced from acetyl-CoA. Most is enzymatically converted to beta-ketobutyrate, but a small amount is spontaneously decarboxylated to acetone. The ketone bodies can be used as fuels by muscle and brain tissue. In starvation and uncontrolled diabetes mellitus, large quantities are produced, causing metabolic acidosis and elevated blood and urine levels of all three ketone bodies. (Dorland, 28th ed)

Registry Number: 0

Descriptor UI: D007657

Alternative terms: Ketone Bodies; Bodies, Ketone; Acetone Bodies; Bodies, Acetone;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis;

Tree Number: D02.522.585;

Technical Notes: acetonemia, acetonuria, ketonemia & ketonuria go here; ketogenesis is probably KETONE BODIES /biosyn