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Killer Cells, Natural - Chemistry
Research News and Information
Definition of 'Killer Cells, Natural'Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T-CELLS and B-CELLS, NK cells are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type. |
Sunday, November 22, 2009
8 Jun 2009
It has been reported that patients with "chronic Lyme disease" have a decreased number of natural killer cells, as defined by the CD57 marker. We performed immunophenotyping in 9 individuals with post-Lyme disease syndrome, 12 who recovered from ... Read more...
Model-free feedback design for a mixed cancer therapy.
29 Apr 2009
In this article, a model-free feedback control design is proposed for the drug administration in mixed cancer therapy. This strategy is very attractive because of the important issue of parameter uncertainties unavoidable when dealing with ... Read more...
10 Jan 2009
Chemokines and their receptors orchestrate leukocyte recruitment and confer immunity during Mycobacterium tuberculosis infection. The immunoregulatory and cytotoxic activities of natural killer (NK) cells are essential at the site of infection ... Read more...
Latest indexed articles for 'Killer Cells, Natural - Chemistry'
These are the very latest articles for this heading:
- Natural killer cell counts are not different between patients with post-Lyme disease syndrome and controls.
8 Jun 2009 - Model-free feedback design for a mixed cancer therapy.
29 Apr 2009 - Differential upregulation of chemokine receptors on CD56 NK cells and their transmigration to the site of infection in tuberculous pleurisy.
10 Jan 2009 - Primary intestinal intraepithelial natural killer-like T-cell lymphoma: case report of a distinct clinicopathologic entity.
30 Dec 2008 - Increased frequency of CD56Bright NK-cells, CD3-CD16+CD56- NK-cells and activated CD4+T-cells or B-cells in parallel with CD4+CDC25High T-cells control potentially viremia in blood donors with HCV.
30 Dec 2008 - Association of monoclonal expansion of Epstein-Barr virus-negative CD158a+ NK cells secreting large amounts of gamma interferon with hemophagocytic lymphohistiocytosis.
17 Nov 2008 - Immuno-modulatory effects of relaxation training and guided imagery in women with locally advanced breast cancer undergoing multimodality therapy: a randomised controlled trial.
10 Nov 2008 - CD34+ hemopoietic precursor and stem cells traffic in peripheral blood of celiac patients is significantly increased but not directly related to epithelial damage severity.
30 Oct 2008 - Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function.
11 Oct 2008 - Critical and differential roles of NKp46- and NKp30-activating receptors expressed by uterine NK cells in early pregnancy.
30 Aug 2008 - Histopathologic and molecular aspects of CD56+ natural killer/ T-cell lymphoma of the testis.
29 Jun 2008 - CD16+ CD56- NK cells in the peripheral blood of cord blood transplant recipients: a unique subset of NK cells possibly associated with graft-versus-leukemia effect.
17 Mar 2008 - Natural killer cells infiltrating human nonsmall-cell lung cancer are enriched in CD56 bright CD16(-) cells and display an impaired capability to kill tumor cells.
13 Feb 2008 - Killer cell immunoglobulin-like receptors on NK cells: the how, where and why.
16 Dec 2007 - Increased NKG2A found in cytotoxic natural killer subset in HIV-1 patients with advanced clinical status.
29 Nov 2007 - Chicken C-type lectin-like receptor B-NK, expressed on NK and T cell subsets, binds to a ligand on activated splenocytes.
20 Oct 2007 - Serum mannose-binding lectin levels are linked with respiratory syncytial virus (RSV) disease.
18 Oct 2007 - Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
16 Oct 2007 - Natural killer cell activation and modulation of chemokine receptor profile in vitro by an extract from the cyanophyta Aphanizomenon flos-aquae.
30 Aug 2007 - A novel multiparametric flow cytometry-based cytotoxicity assay simultaneously immunophenotypes effector cells: comparisons to a 4 h 51Cr-release assay.
26 Jun 2007
See a longer list of these articles.
Technical information about 'Killer Cells, Natural'
Definition: Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T-CELLS and B-CELLS, NK cells are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
Descriptor UI: D007694
Alternative terms: Killer Cells, Natural; Natural Killer Cells; Cell, Natural Killer; Cells, Natural Killer; Killer Cell, Natural; Natural Killer Cell; NK Cells; Cell, NK; Cells, NK; NK Cell;
Related Mesh Headings: Receptors, Natural Killer Cell;
Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;
Tree Number: A11.118.637.555.567.537; A15.145.229.637.555.567.537; A15.382.490.555.567.537;
History Note: 1983
Technical Notes: do not confuse with NATURAL KILLER T-CELLS; if subpopulations are discussed, coordinate IM with LYMPHOCYTE SUBSETS (IM)