Kleine-Levin Syndrome - Diagnosis
Research News and Information

Sunday, November 22, 2009

Gabapentin for Kleine-Levin syndrome.

29 Jun 2009 We describe a 17-year-old girl with Kleine-Levin syndrome (KLS), in which gabapentin was effective for the prevention of attacks. (99)mTc-ECD SPECT revealed hyperperfusion of the thalamus and nucleus accumbens presenting in the symptomatic period, ... Read more...

Working memory in 8 Kleine-Levin syndrome patients: an fMRI study.

29 Apr 2009 STUDY OBJECTIVES: The objectives of this study were to investigate possible neuropathology behind the Kleine-Levin Syndrome (KLS), a severe form of hypersomnia with onset during adolescence. DESIGN: Functional magnetic resonance imaging (fMRI) ... Read more...

Kleine-Levin syndrome.

30 Jan 2009 Kleine-Levin syndrome, sometimes referred to as Rip van Winkle disease, is a rare sleep disorder mainly affecting teenage boys in which the main features are intermittent hypersomnolence, behavioural and cognitive disturbances, hyperphagia and in ... Read more...

Latest indexed articles for 'Kleine-Levin Syndrome - Diagnosis'

These are the very latest articles for this heading:

• Gabapentin for Kleine-Levin syndrome. 29 Jun 2009
• Working memory in 8 Kleine-Levin syndrome patients: an fMRI study. 29 Apr 2009
• Kleine-Levin syndrome. 30 Jan 2009
• Kleine-Levin syndrome. 29 Nov 2008
• [Kleine-Levin syndrome. A description of a case in a teenage girl] 30 Aug 2008
• Sarcoidosis: a rare cause of Kleine-Levine-Critchley syndrome. 30 Aug 2008
• Diagnostic pitfalls in children with sleep disorders: two cases with hypersomnia. 25 Aug 2008
• [Kleine-Levin syndrome: state of the art] 21 Jul 2008
• Polysomnography in Kleine-Levin syndrome. 2 Mar 2008
• Episodic hypersomnia and unusual behaviors in a 14-year old adolescent. 29 Nov 2007
• Lower dopamine transporter density in an asymptomatic patient with Kleine-Levin syndrome. 18 Nov 2007
• Magnetic resonance spectroscopy in a patient with Kleine-Levin syndrome. 13 Oct 2007
• Atypical Kleine--Levin syndrome: can insomnia and anorexia be features too? 18 Jul 2007
• Kleine-Levin syndrome mimicking mania. 29 Apr 2007
• Kleine-Levin syndrome: interface between neurology and psychiatry. 27 Feb 2007
• Posttraumatic Kleine-Levin syndrome. 30 Aug 2006
• [Kleine-Levin syndrome] 26 May 2006
• SPECT findings in the Kleine-Levin syndrome. 30 Jul 2005
• The Kleine-Levin syndrome: a paramedian thalamic dysfunction? 30 Jul 2005
• Kleine-Levin syndrome: a unique cause of fatigue in an athlete. 30 Jan 2005

See a longer list of these articles.

Technical information about 'Kleine-Levin Syndrome'

Definition: A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)

Descriptor UI: D017593

Alternative terms: Kleine-Levin Syndrome; Kleine Levin Syndrome; Syndrome, Kleine-Levin; Kleine-Levin-Critchley Syndrome; Kleine Levin Critchley Syndrome; Syndrome, Kleine-Levin-Critchley; Hypersomnia, Periodic; Periodic Hypersomnia; Periodic Hypersomnias;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.886.425.800.200.500; F03.870.400.800.200.500;

History Note: 94