Kleine-Levin Syndrome - Physiopathology
Research News and Information

Sunday, November 22, 2009

Gabapentin for Kleine-Levin syndrome.

29 Jun 2009 We describe a 17-year-old girl with Kleine-Levin syndrome (KLS), in which gabapentin was effective for the prevention of attacks. (99)mTc-ECD SPECT revealed hyperperfusion of the thalamus and nucleus accumbens presenting in the symptomatic period, ... Read more...

A case of Kleine-Levin syndrome with a complete and sustained response to carbamazepine.

14 Jun 2009 We describe a patient with Kleine-Levin syndrome who was initially misdiagnosed as having epilepsy and who achieved complete remission on carbamazepine treatment. A drug effect was established when symptoms recurred after carbamazepine taper and ... Read more...

[Kleine-Levin syndrome]

29 Apr 2009 KLeine-Levin Syndrome (KLS) is a rare disease characterized by recurrent episodes of hypersomnia associated with cognitive and behavioral disturbances, compulsive eating behavior and hypersexuality. Episodes are separated by weeks or months of ... Read more...

Latest indexed articles for 'Kleine-Levin Syndrome - Physiopathology'

These are the very latest articles for this heading:

• Gabapentin for Kleine-Levin syndrome. 29 Jun 2009
• A case of Kleine-Levin syndrome with a complete and sustained response to carbamazepine. 14 Jun 2009
• [Kleine-Levin syndrome] 29 Apr 2009
• Working memory in 8 Kleine-Levin syndrome patients: an fMRI study. 29 Apr 2009
• Kleine-Levin syndrome. 30 Jan 2009
• An adult onset patient with Kleine-Levin syndrome responding to valproate. 2 Dec 2008
• [Kleine-Levin syndrome. A description of a case in a teenage girl] 30 Aug 2008
• Kleine-Levin syndrome: history and brief review. 28 Jul 2008
• Polysomnography in Kleine-Levin syndrome. 2 Mar 2008
• Atypical Kleine--Levin syndrome: can insomnia and anorexia be features too? 18 Jul 2007
• Hypocretin/Orexin: a molecular link between sleep, energy regulation, and pleasure. 30 Dec 2006
• Episodic diencephalic hypoperfusion in Kleine-Levin syndrome. 30 Jul 2006
• [Kleine-Levin syndrome] 26 May 2006
• SPECT findings in the Kleine-Levin syndrome. 30 Jul 2005
• The Kleine-Levin syndrome: a paramedian thalamic dysfunction? 30 Jul 2005
• Short-term memory dysfunction in Kleine-Levin syndrome. 30 Oct 2003
• Photosensitivity during the hypersomnic phase in a patient with Kleine-Levin syndrome. 30 May 2003
• Persistent neuropsychological deficits in the Kleine-Levin syndrome. 30 Mar 2003
• [Kleine-Levin syndrome: diagnostic contribution made by brain SPECT] 27 Feb 2003
• Familial Kleine-Levin syndrome: two siblings with unusually long hypersomnic spells. 29 Nov 2002

See a longer list of these articles.

Technical information about 'Kleine-Levin Syndrome'

Definition: A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)

Descriptor UI: D017593

Alternative terms: Kleine-Levin Syndrome; Kleine Levin Syndrome; Syndrome, Kleine-Levin; Kleine-Levin-Critchley Syndrome; Kleine Levin Critchley Syndrome; Syndrome, Kleine-Levin-Critchley; Hypersomnia, Periodic; Periodic Hypersomnia; Periodic Hypersomnias;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.886.425.800.200.500; F03.870.400.800.200.500;

History Note: 94