Kleine-Levin Syndrome
Research News and Information

Sunday, November 22, 2009

Gabapentin for Kleine-Levin syndrome.

29 Jun 2009 We describe a 17-year-old girl with Kleine-Levin syndrome (KLS), in which gabapentin was effective for the prevention of attacks. (99)mTc-ECD SPECT revealed hyperperfusion of the thalamus and nucleus accumbens presenting in the symptomatic period, ... Read more...

A case of Kleine-Levin syndrome with a complete and sustained response to carbamazepine.

14 Jun 2009 We describe a patient with Kleine-Levin syndrome who was initially misdiagnosed as having epilepsy and who achieved complete remission on carbamazepine treatment. A drug effect was established when symptoms recurred after carbamazepine taper and ... Read more...

[Kleine-Levin syndrome]

29 Apr 2009 KLeine-Levin Syndrome (KLS) is a rare disease characterized by recurrent episodes of hypersomnia associated with cognitive and behavioral disturbances, compulsive eating behavior and hypersexuality. Episodes are separated by weeks or months of ... Read more...

Latest indexed articles for 'Kleine-Levin Syndrome'

These are the very latest articles for this heading:

• Gabapentin for Kleine-Levin syndrome. 29 Jun 2009
• A case of Kleine-Levin syndrome with a complete and sustained response to carbamazepine. 14 Jun 2009
• [Kleine-Levin syndrome] 29 Apr 2009
• Working memory in 8 Kleine-Levin syndrome patients: an fMRI study. 29 Apr 2009
• Pharmacological treatment for Kleine-Levin Syndrome. 13 Apr 2009
• Kleine-Levin syndrome. 30 Jan 2009
• Lithium prophylaxis in Kleine-Levin syndrome. 30 Dec 2008
• An adult onset patient with Kleine-Levin syndrome responding to valproate. 2 Dec 2008
• Kleine-Levin syndrome. 29 Nov 2008
• Sibutramine-induced psychotic episode in an adolescent. 30 Oct 2008
• [Kleine-Levin syndrome. A description of a case in a teenage girl] 30 Aug 2008
• Sarcoidosis: a rare cause of Kleine-Levine-Critchley syndrome. 30 Aug 2008
• Diagnostic pitfalls in children with sleep disorders: two cases with hypersomnia. 25 Aug 2008
• Kleine-Levin syndrome: history and brief review. 28 Jul 2008
• [Kleine-Levin syndrome: state of the art] 21 Jul 2008
• A case of late-onset Kleine-Levin syndrome responding to lamotrigine. 27 May 2008
• Influenza-associated central nervous system dysfunction: a literature review. 5 May 2008
• Kleine-Levin syndrome: a systematic study of 108 patients. 30 Mar 2008
• Polysomnography in Kleine-Levin syndrome. 2 Mar 2008
• Episodic hypersomnia and unusual behaviors in a 14-year old adolescent. 29 Nov 2007

See a longer list of these articles.

Technical information about 'Kleine-Levin Syndrome'

Definition: A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)

Descriptor UI: D017593

Alternative terms: Kleine-Levin Syndrome; Kleine Levin Syndrome; Syndrome, Kleine-Levin; Kleine-Levin-Critchley Syndrome; Kleine Levin Critchley Syndrome; Syndrome, Kleine-Levin-Critchley; Hypersomnia, Periodic; Periodic Hypersomnia; Periodic Hypersomnias;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.886.425.800.200.500; F03.870.400.800.200.500;

History Note: 94