Lac Operon
Research News and Information

Sunday, November 22, 2009

Thrombospondin-2 therapy ameliorates experimental glomerulonephritis via inhibition of cell proliferation, inflammation, and TGF-beta activation.

31 Aug 2009 We recently identified thrombospondin-2 (TSP-2) as an endogenous regulator of matrix remodelling and inflammation in experimental kidney disease by studying TSP-2-deficient mice. In this study, we asked whether systemic TSP-2 overexpression via ... Read more...

Efficient exact and K-skip methods for stochastic simulation of coupled chemical reactions.

12 Aug 2009 Gillespie's direct method (DM) [D. Gillespie, J. Chem. Phys. 81, 2340 (1977)] for exact stochastic simulation of chemical reaction systems has been widely adopted. It is easy to implement but requires large computation for relatively large systems. ... Read more...

In vivo optical imaging of LacZ expression using lacZ transgenic mice.

30 Jul 2009 beta-Galactosidase (beta-gal) (encoded by the lacZ gene) has been widely used as a transgene reporter enzyme. The ability to image lacZ expression in living transgenic animals would further extend the use of this reporter. It has been reported that ... Read more...

Latest indexed articles for 'Lac Operon'

These are the very latest articles for this heading:

• Thrombospondin-2 therapy ameliorates experimental glomerulonephritis via inhibition of cell proliferation, inflammation, and TGF-beta activation. 31 Aug 2009
• Efficient exact and K-skip methods for stochastic simulation of coupled chemical reactions. 12 Aug 2009
• In vivo optical imaging of LacZ expression using lacZ transgenic mice. 30 Jul 2009
• Mathematical biology education: beyond calculus. 29 Jul 2009
• Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm. 2 Jul 2009
• Stem cell aging and aberrant differentiation within the niche. 30 Jun 2009
• Unfolding evolution: from transposons and the Cambrian explosion to the function of the enigmatic lacA gene. 29 Jun 2009
• Cells need safety valves. 29 Jun 2009
• The absence of angiopoietin-2 leads to abnormal vascular maturation and persistent proliferative retinopathy. 29 Jun 2009
• LysR family transcriptional regulator PqsR as repressor of pyoluteorin biosynthesis and activator of phenazine-1-carboxylic acid biosynthesis in Pseudomonas sp. M18. 15 Jun 2009
• Leptin targets in the mouse brain. 8 Jun 2009
• Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice. 6 Jun 2009
• Cre/lox recombination in the lower urinary tract. 30 May 2009
• Utility of HoxB2 enhancer-mediated Cre activity for functional studies in the developing inner ear. 30 May 2009
• Transposon-directed base-exchange mutagenesis (TDEM): a novel method for multiple-nucleotide substitutions within a target gene. 30 May 2009
• A simple technique to establish a long-term adenovirus mediated gene transfer to the heart of newborn mice. 30 May 2009
• Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging. 27 May 2009
• A single exposure to an enriched environment stimulates the activation of discrete neuronal populations in the brain of the fos-tau-lacZ mouse. 16 May 2009
• Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins. 13 May 2009
• Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice. 4 May 2009

See a longer list of these articles.

Technical information about 'Lac Operon'

Definition: The genetic unit consisting of three structural genes, an operator and a regulatory gene. The regulatory gene controls the synthesis of the three structural genes: BETA-GALACTOSIDASE and beta-galactoside permease (involved with the metabolism of lactose), and beta-thiogalactoside acetyltransferase.

Descriptor UI: D007763

Alternative terms: Lac Operon; Lac Operons; Operon, Lac; Operons, Lac; Lactose Operon; Lactose Operons; Operon, Lactose; Operons, Lactose; LacZ Genes; Gene, LacZ; Genes, LacZ; LacZ Gene; Lac Gene; Gene, Lac; Genes, Lac; Lac Genes;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.360.340.024.686.545; G05.360.340.300.500.545;

History Note: 79

Technical Notes: note category; consider also LAC REPRESSORS (see note on REPRESSOR PROTEINS)